Results 61 to 70 of about 367,224 (266)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A constraint–relaxation–recovery mechanism for stomatal dynamics [PDF]
Plant, Cell & Environment, 2019 AbstractModels of guard cell dynamics, built on the OnGuard platform, have provided quantitative insights into stomatal function, demonstrating substantial predictive power. However, the kinetics of stomatal opening predicted by OnGuard models were threefold to fivefold slower than observed in vivo.
Mareike Jezek +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Computational Analysis of Self-Healing in Nanomaterials Using Neural Spike Algorithms
InformationThis computational study investigates dynamic self-healing processes in nanomaterials driven by neuronal spike activity. We developed a multiscale simulation framework that integrates neuronal dynamics, quantum mechanical effects, and material science ...
Jongho Seol +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Cailiao gongcheng, 2020 The thermal compression experiment of TB17 titanium alloy in the β phase region was carried out by Gleeble-3800 hot compression simulator. The dynamic recrystallization behavior and transformation mechanism in the β phase region of the TB17 titanium ...
ZHU Hong-chang +2 more
doaj
Environmental Research Letters, 2022 Optimizing the allocation schemes of post-disaster recovery resources can promote the sustainable development of a regional economy. However, previous studies determined the inputs and allocation schemes of recovery resources based on direct economic (DE)
Hongwei Li +3 more
doaj +1 more source
A Nonconvex Framework for Structured Dynamic Covariance Recovery
CoRR, 2020 We propose a flexible yet interpretable model for high-dimensional data with time-varying second order statistics, motivated and applied to functional neuroimaging data. Motivated by the neuroscience literature, we factorize the covariances into sparse spatial and smooth temporal components. While this factorization results in both parsimony and domain
Katherine Tsai +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Spontaneous recovery in dynamical networks [PDF]
Nature Physics, 2013 Much research has been carried out to explore the structural properties and vulnerability of complex networks. Of particular interest are abrupt dynamic events that cause networks to irreversibly fail. However, in many real-world phenomena, such as brain seizures in neuroscience or sudden market crashes in finance, after an inactive period of time a ...
Majdandzic Antonio +5 more
openaire +1 more source