Results 61 to 70 of about 370,697 (266)
Journal of the American Statistical Association (2023)
Ziyuan Chen, Ying Yang, Fang Yao
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A Nonconvex Framework for Structured Dynamic Covariance Recovery
We propose a flexible yet interpretable model for high-dimensional data with time-varying second order statistics, motivated and applied to functional neuroimaging data. Motivated by the neuroscience literature, we factorize the covariances into sparse spatial and smooth temporal components. While this factorization results in both parsimony and domain
Katherine Tsai +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
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The thermal compression experiment of TB17 titanium alloy in the β phase region was carried out by Gleeble-3800 hot compression simulator. The dynamic recrystallization behavior and transformation mechanism in the β phase region of the TB17 titanium ...
ZHU Hong-chang +2 more
doaj
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Dynamic VAR planning methodology to enhance transient voltage stability for failure recovery
In recent years, failure recovery after faults is concerned and discussed worldwide as an important and hot topic. Facing the challenge of heavy loads and ultra-high voltage transmission, it’s urgent to propose some solutions to enhance transient voltage
Di YANG +4 more
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Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Resource Constrained Project Scheduling With Dynamic Disruption Recovery
Resource-constrained project scheduling is one of the most widely studied research problems. Although a large number of algorithms have been developed for solving these problems, many of them ignored several practical issues such as resource ...
Forhad Zaman +3 more
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
DYNAMICAL RECOVERY AND DIFFUSION
Plastic deformation techniques can be applied to investigate self-diffusion in Si and Ge. By this way, activation energies of 2.8 eV and 3.6 eV for Ge and Si, respectively, were deduced. For Si, the pre-exponential factor Do was estimated to be 0.5 cm2/s. These results are discussed in terms of diffusion by a monovacancy mechanism.
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