Results 81 to 90 of about 367,224 (266)

Resource Constrained Project Scheduling With Dynamic Disruption Recovery

IEEE Access, 2020
Resource-constrained project scheduling is one of the most widely studied research problems. Although a large number of algorithms have been developed for solving these problems, many of them ignored several practical issues such as resource ...
Forhad Zaman, Saber M. Elsayed, Ruhul Saker, Daryl Essam   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Dynamic Recovery: GABA Agonism Restores Neural Variability in Older, Poorer Performing Adults. [PDF]

J Neurosci, 2021
Lalwani P, Garrett DD, Polk TA.
europepmc   +1 more source

Robust Spectral Recovery for Dynamical Sampling

CoRR
We study the spectral recovery problem for dynamical sampling on a finite cyclic grid. Given time snapshots obtained from a fixed uniform spatial subsampling of the orbit $x_{\ell}=A^{\ell}f$, we aim to recover the spectrum of the unknown circular convolution operator $A$.
HanQin Cai, Longxiu Huang, Tianming Wang, Juntao You   +3 more
openaire   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Hot deformation and microstructure evolution of TiZrAlHf Ti-based medium entropy alloy

Cailiao gongcheng
In order to optimize the hot working window of the novel TiZrAlHf Ti-based medium entropy alloy, the thermal deformation characteristics and microstructural evolution during thermal deformation were investigated by using hot compression simulation ...
LIU Qianqian, YANG Xiaoyu, GAO Fan, LI Zhenxi, LIU Hongwu, WANG Qingfeng   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Boosting the mechanical properties at 815°C of laser-directed energy-deposited Inconel 625 alloy by introducing the Laves phase

Virtual and Physical Prototyping
This study aims to enhance the high-temperature mechanical properties of the laser-directed energy-deposited Inconel 625 alloy. Varied sizes, morphologies and volume fractions of the Laves phase were effectively regulated, high-temperature tensile ...
Zuo Li, Xin Lin, Xin Hou, Zhiwei Hao, Wei Fan, Chongliang Zhong, Hua Tan, Yiyi Zhou, Yi Min Xie   +8 more
doaj   +1 more source

Pediatric Multi-Organ Dysfunction Syndrome: Analysis by an Untargeted "Shotgun" Lipidomic Approach Reveals Low-Abundance Plasma Phospholipids and Dynamic Recovery over 8-Day Period, a Single-Center Observational Study. [PDF]

Nutrients, 2021
Leimanis-Laurens ML, Ferguson K, Wolfrum E, Boville B, Sanfilippo D, Lydic TA, Prokop JW, Rajasekaran S.   +7 more
europepmc   +1 more source