Results 91 to 100 of about 1,338,644 (306)

Resource Constrained Project Scheduling With Dynamic Disruption Recovery

IEEE Access, 2020
Resource-constrained project scheduling is one of the most widely studied research problems. Although a large number of algorithms have been developed for solving these problems, many of them ignored several practical issues such as resource ...
Forhad Zaman, Saber M. Elsayed, Ruhul Saker, Daryl Essam   +3 more
doaj   +1 more source

A hybrid CPU-GPU parallelization scheme of variable neighborhood search for inventory optimization problems

, 2017
In this paper, we study various parallelization schemes for the Variable Neighborhood Search (VNS) metaheuristic on a CPU-GPU system via OpenMP and OpenACC.
Antoniadis, Nikolaos, Sifaleras, Angelo
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

An engineering approach to modelling of dynamic insulation using ESP-r [PDF]

, 2003
The use of Dynamic Insulation (DI) can enable recovery of conduction heat loss through a building envelope. This is an active process that allows air to move through the fabric against the temperature gradient.
Imbabi, M., Peacock, A., Samuel, A.A.A., Strachan, P.A., Strachan, Paul   +4 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Dynamic Recovery: GABA Agonism Restores Neural Variability in Older, Poorer Performing Adults. [PDF]

J Neurosci, 2021
Lalwani P, Garrett DD, Polk TA.
europepmc   +1 more source

Economic Recovery in the Euro Area and in Austria in a Dynamic Global Economic Environment [PDF]

Economic Recovery in the Euro Area and in Austria in a Dynamic Global Economic EnvironmentEconomic ...
Antje Hildebrandt, Maria Antoinette Silgoner, Martin Schneider   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Hot deformation and microstructure evolution of TiZrAlHf Ti-based medium entropy alloy

Cailiao gongcheng
In order to optimize the hot working window of the novel TiZrAlHf Ti-based medium entropy alloy, the thermal deformation characteristics and microstructural evolution during thermal deformation were investigated by using hot compression simulation ...
LIU Qianqian, YANG Xiaoyu, GAO Fan, LI Zhenxi, LIU Hongwu, WANG Qingfeng   +5 more
doaj   +1 more source