Results 121 to 130 of about 3,923,177 (307)
Seismic Response Analysis of Concrete Box-Type Subgrade in High-Speed Railways
Applied SciencesChina is prone to frequent earthquakes, impacting both the construction and operation of high-speed railways. The seismic response analysis is essential for the promotion and structural optimization of novel box-type subgrade structures.
Ying-Ying Chen +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Frontiers in MaterialsIn this study, forced vibration analysis of an energy pile with non-uniformity in vertically inhomogeneous soil is presented considering the non-uniform distributed temperature.
Zhuanzhuan Zhang, Zhao Lu, Zhao Lu
doaj +1 more source
Drive train dynamic analysis [PDF]
A method for parametric variations in drive train dynamic analysis is described. The method models the individual components of a drive system, forms the appropriate system interface coordinates and, calculates the system dynamic response at particular ...
Giansante, N.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Simulation Analysis of Seismic Response of Long-distance Suspended Pipeline
Shiyou jixie, 2017 In order to study the dynamic response of the long-distance suspended pipeline under the action of seismic load, the general finite element software ABAQUS has been used to conduct numerical simulation.
Lei Zhen +3 more
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Applied SciencesWith the rapid expansion of high-speed railway (HSR) networks, the vibration impact on adjacent energy infrastructure has become a critical safety concern.
Meibao Chen +5 more
doaj +1 more source
New broadband square-law detector [PDF]
, 1975 Compact device has wide dynamic range, accurate square-law response, good thermal stability, high-level dc output with immunity to ground-loop problems, ability to insert known time constants for radiometric applications, and fast response times ...
Gardner, R. A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source