Results 121 to 130 of about 1,370,654 (308)
Applied SciencesWith the rapid expansion of high-speed railway (HSR) networks, the vibration impact on adjacent energy infrastructure has become a critical safety concern.
Meibao Chen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Applied SciencesBlast-induced vibrations from newly constructed tunnels may adversely affect adjacent existing tunnel structures. To ensure the safety of the existing tunnel, it is essential to investigate its dynamic response under blast disturbances.
Youxin Shao +5 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Study on Drill String Fatigue Life in Deepwater Drilling
Shiyou jixie, 2016 Dynamic response of the deepwater drilling platform increases alternating loads of the drilling string.As a consequence,the calculation of drill string fatigue life becomes more complicated.By using the numerical simulation method,a method for studying ...
Wang Jiajia, Chen Jianmin
doaj
Applied SciencesPumped-storage power stations (PSPSs) are vital for grid stability, yet pump-turbines (PTs) operating in the S-shaped region often induce severe hydraulic instability.
Yutong Mao +4 more
doaj +1 more source
Seasonal price premiums have been proposed as a means of dampening the highly seasonal patterns of milk production in Florida. A Markov decision bio-economic model of the breeding and replacement decisions was solved via stochastic dynamic programming ...
Delorenzo, Michael A. +2 more
core
Nonlinear Dynamic Response of Tension Leg Platform
, 2006 Tension Leg Platform (TLP) is a typical compliant offshore structure for oil exploitation in deep water. Most of the existing mathematical models for analyzing the dynamic response of TLP are based on explicit or implicit assumptions that displacements ...
Zeng XH(曾晓辉) +4 more
core
A Completely Scalable Lumped-Circuit Model for Horizontal and Vertical HALL Devices
, 2007 A completely scalable lumped-circuit model for horizontal and vertical HALL devices is presented therein that can be efficiently implemented in SPICE-like EDA simulators.
Reymond, S +14 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source