Results 41 to 50 of about 3,118,026 (239)
QoS in Node-disjoint Routing for Ad Hoc Networks [PDF]
PhDA mobile ad hoc network (MANET) is a collection of mobile nodes that can communicate with each other without using any fixed infrastructure. It is necessary for MANETs to have efficient routing protocol and quality of service (QoS) mechanism to ...
Liu, Luo
core +4 more sources
Dynamic multicast routing in software-defined networks is challenging due to continuously changing network states, multicast branch coupling, and the dependency between local forwarding decisions and global multicast tree construction. Existing multicast
Peiying Zhang +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The paper describes new developments of a multiple objective dynamic routing method (MODR) for circuit-switched networks previously presented, based on the periodic calculation of alternative paths for every node pair by a specialised bi-objective ...
Lúcia Martins
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Location-Routing: Issues, Models and Methods [PDF]
This paper is a survey of location-routing: a relatively new branch of locational analysis that takes into account vehicle routing aspects. We propose a classification scheme and look at a number of problem variants. Both exact and heuristic algorithms
Gábor Nagy +3 more
core +1 more source
Hierarchical Load-Balanced Routing Optimization for Mega-Constellations via Geographic Partitioning
Large-scale Low Earth Orbit (LEO) satellite constellations have become critical infrastructure for global communications, yet routing optimization remains challenging.
Guinian Feng +3 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source

