Results 31 to 40 of about 65,605 (245)

Dynamic shear rupture of steel plates [PDF]

open access: yesJournal of Mechanics of Materials and Structures, 2007
Metallic sandwich panels with prismatic cores offer the potential for superior blast resistance relative to monolithic plates of equivalent areal density. However, under sufficiently high impulse, severe plastic strains can occur at the junctions of the face sheets and the core members shortly after arrival of the pressure wave but prior to significant
Ken Nahshon   +4 more
openaire   +1 more source

INFLUENCE OF HILLS AND VALLEYS ON FREE SURFACE SLIP AMPLIFICATION IN DYNAMIC RUPTURE ON A DIPPING FAULT

open access: yesГеодинамика и тектонофизика
Dynamic rupture scenarios on various fault geometries are studied extensively in the literature for domains with the planar top surface. However, landscapes on the earth, particularly in tectonic regimes, can undulate upwards or downwards depending on ...
R. Parla, S. N. Somala
doaj   +1 more source

How the Transition Region Along the Cascadia Megathrust Influences Coseismic Behavior: Insights From 2‐D Dynamic Rupture Simulations

open access: yesGeophysical Research Letters, 2019
There is a strong need to model potential rupture behaviors for the next Cascadia megathrust earthquake. However, there exists significant uncertainty regarding the extent of downdip rupture and rupture speed.
Marlon D. Ramos, Yihe Huang
doaj   +1 more source

Dynamic rupture along bimaterial interfaces in 3D

open access: yesGeophysical Research Letters, 2007
We perform numerical simulations of dynamic rupture propagation on a plane in a model consisting of two different elastic half spaces connected via a planar frictional interface governed by regularized Coulomb friction. Therefore, ruptures in this study are purely driven by the presence of a material contrast.
Brietzke, G., Cochard, A., Igel, H.
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Dynamic rupture of polymer–metal bilayer plates

open access: yesInternational Journal of Solids and Structures, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
McShane, G.J.   +5 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Intraoperative rupture cerebral aneurysm and computational flow dynamics

open access: yesAsian Journal of Neurosurgery, 2018
Intraoperative aneurysmal rupture (IAR) is the most fearsome complication of aneurysm surgery. IAR associates with high morbidity and mortality. In recent years, we have many studies regarding using computational fluid dynamics (CFD) in aneurysm surgery.
Senko, Ilya   +7 more
openaire   +3 more sources

Ultrafast ultrasound captures dynamic rupture behavior [PDF]

open access: yesProceedings of Meetings on Acoustics, 2018
We apply shear wave elastography, a medical imaging technique that uses ultrafast ultrasound to analyze rupture nucleation. In order to better understand friction and rupture processes which are responsible for earthquake nucleation, we build a laboratory experiment that reproduces the stick-slip behavior of a seismic fault for soft elastic materials ...
Aichele, Johannes   +4 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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