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By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Multi-agent system for dynamic manufacturing system optimization [PDF]
, 2008 This paper deals with the application of multi-agent system concept for optimization of dynamic uncertain process. These problems are known to have a computationally demanding objective function, which could turn to be infeasible when large problems are ...
A.J. Gonzalez +6 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Dynamic scheduling of process groups
Concurrency: Practice and Experience, 1998 Summary: We introduce the concept of temporal locality of communication for process groups and a hierarchical decision model for dynamic scheduling of process groups. Empirical evidence suggests that, once a member of a process group starts to communicate with other processes in the group, it will continue to do so, while an independent process will ...
Wang, Kuei Yu +2 more
openaire +5 more sources
A Dynamic Scheduling Method for Logistics Tasks Oriented to Intelligent Manufacturing Workshop
Mathematical Problems in Engineering, 2019 Aiming at the logistics dynamic scheduling problem in an intelligent manufacturing workshop (IMW), an intelligent logistics scheduling model and response method with Automated Guided Vehicles (AGVs) based on the mode of “request-scheduling-response” were
Wenxiang Xu +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Automated generation of dispatching rules for the green unrelated machines scheduling problem
Complex & Intelligent SystemsThe concept of green scheduling, which deals with the environmental impact of the scheduling process, is becoming increasingly important due to growing environmental concerns.
Nikolina Frid +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The Impact of Data Replicatino on Job Scheduling Performance in Hierarchical data Grid
, 2010 In data-intensive applications data transfer is a primary cause of job execution delay. Data access time depends on bandwidth. The major bottleneck to supporting fast data access in Grids is the high latencies of Wide Area Networks and Internet ...
Abdi, Somayeh +2 more
core +2 more sources