Results 81 to 90 of about 5,828,755 (297)

Nonlinear Model Predictive Control for a Dynamic Positioning Ship Based on the Laguerre Function

open access: yesJournal of Marine Science and Engineering
In this paper, we present a novel nonlinear model predictive control (NMPC) algorithm based on the Laguerre function for dynamic positioning ships to solve the problems of input saturation, unknown time-varying disturbances, and heavy computation.
Xiaobin Qian   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Simulation of the dynamics of hard ellipsoids [PDF]

open access: yesPhilosophical Magazine, 2008
We study a system of uniaxial hard ellipsoids by molecular dynamics simulations, changing both the aspect-ratio X0 and the packing fraction PHI. We calculate the translational and rotational mean squared displacements, the translational and the rotational diffusion coefficients and the associated isodiffusivity lines in the PHI-X0 plane.
DE MICHELE, CRISTIANO   +2 more
openaire   +5 more sources

Pantograph catenary dynamic optimisation based on advanced multibody and finite element co-simulation tools [PDF]

open access: yes, 2013
This paper presents recent developments undertaken by the SNCF Innovation & Research Department on numerical modelling of pantograph catenary interaction. It aims at describing an efficient co-simulation process between finite element (FE) and multibody (
BALMES, Etienne   +4 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Conformational Dynamics Simulations of Proteins [PDF]

open access: yes, 1999
Molecular dynamics (MD) simulations of proteins provide descriptions of atomic motions, which allow to relate observable properties of proteins to microscopic processes. Unfortunately, such MD simulations require an enormous amount of computer time and, therefore, are limited to time scales of nanoseconds.
Eichinger, Markus   +10 more
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Multiple strut-deformation patterns based analytical elastic modulus of sandwich BCC lattices

open access: yesMaterials & Design, 2019
This paper proposed an analytical methodology to predict the mechanical properties of sandwich body-centred cubic (BCC) lattice structures. Based on the Timoshenko beam theory, the multiple strut-deformation patterns were first introduced in the ...
Yunhui Yang   +4 more
doaj   +1 more source

The effects of numerical acceleration techniques on PIC-MCC simulations of ion thrusters

open access: yesAIP Advances, 2020
The particle-in-cell-Monte Carlo collision method has been widely used in simulation studies of ion thrusters. Due to the huge computational demand of such simulations, numerical acceleration techniques are required.
Tiannan Yuan   +5 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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