Results 91 to 100 of about 128,321 (246)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Dynamic Tension Control System for Chain of Scraper Conveyor and Its Applicatio
Gong-kuang zidonghua, 2012 For problem of frequent faults of scraper and chain breakage caused by traditional artificial tension mode for chain of scraper conveyor, the paper introduced composition, working principle and operation mode of a dynamic tension control system for chain
CHEN Ju
doaj
Advances in Mechanical Engineering, 2017 This article demonstrates the tension distribution estimation method for the ring chain transmission system of scraper conveyer, which is based on multi-body dynamics theory and linear state observer. As designed, a multi-body dynamic model of ring chain
Xing Zhang +4 more
doaj +1 more source
X-ray Diffraction Studies on the Structural Origin of Dynamic Tension Recovery Following Ramp-Shaped Releases in High-Ca Rigor Muscle Fibers. [PDF]
Int J Mol Sci, 2020 Sugi H +4 more
europepmc +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
DYNAMIC RESPONSE CALCULATION OF ROD UNDER ECCENTRIC TENSION AND COMPRESSION LOADINGS
Jixie qiangdu, 2016 The bars under tension and compression loadings widely exist in the structural engineering applications,which are the important loaded elements. This is because of the existence of all kinds of installed errors,the bars under tension and compression ...
CHU JunLiang
doaj
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
SEMI-ANALYTUCAL SOLUTION TO DYNAMIC ANALYSIS FOR PLOUGH SYSTEM
Jixie qiangdu, 2018 According to working features of plough system,three sections of visco-elastic dynamic model were established based on wave theory. The boundary conditions,joining conditions and initial condition of wave equation under stable running were determined ...
CHEN Hong Yue +4 more
doaj
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source