Evaluating the feasibility of cognitive impairment detection in Alzheimer's disease screening using a computerized visual dynamic test. [PDF]
J Neuroeng Rehabil, 2023 Perez-Valero E +3 more
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Experimental and numerical determination of tube collision energy absorbers characteristics [PDF]
FME Transactions, 2012 Development of collision energy absorbers is one of the necessary measures for passive safety of passenger coaches. The purpose of passive safety is to minimize the collision consequences for passengers.
Tanasković Jovan D. +3 more
doaj
Pseudo-Dynamic Test on Composite Frame with Steel-Reinforced Recycled Concrete Columns and Steel Beams. [PDF]
Materials (Basel), 2022 Dong J, Cong X, Ma H, Liu Y, Wang Y.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
SensorsWearable strain sensors are widespread in many fields, including the biomedical field where they are used for their stretchability and ability to be applied to non-regular surfaces. The study of the propagation speed of the pressure wave generated by the
Federico Filippi +7 more
doaj +1 more source
Reliability of a novel dynamic test of postural stability in high-level soccer players. [PDF]
Heliyon, 2021 Beelen PE +10 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Study of the Stability of Palletized Cargo by Dynamic Test Method Performed on Laboratory Test Bench. [PDF]
Sensors (Basel), 2021 Tkaczyk S +3 more
europepmc +1 more source