Results 151 to 160 of about 687,920 (318)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Progression and individual differences in children's series completion after dynamic testing. [PDF]
Br J Educ Psychol, 2020 Touw KWJ +4 more
europepmc +1 more source
Unit-root and stationarity testing with empirical application on industrial production of CEE-4 countries [PDF]
The purpose of this paper is to explain both the need and the procedures of unit-root testing to a wider audience. The topic of stationarity testing in general and unit root testing in particular is one that covers a vast amount of research. We have been
Výrost, Tomáš +2 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Simulated driving: The added value of dynamic testing in the assessment of visuo-spatial neglect after stroke. [PDF]
J Neuropsychol, 2020 Spreij LA +3 more
europepmc +1 more source
An investigation of delay fault testing for multi voltage design [PDF]
, 2009 Multi Voltage Design (MVD) has been successfully applied in contemporary processors as a technique to reduce energy consumption. This work is aimed at finding a generalised delay testing method for MVD.
Zain Ali, Noohul Basheer
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
3Was of Static Software Testing Techniques [PDF]
, 2011 No fault detection technique is capable of finding all classes of fault in software, so we have to use variety of techniques that will help us to ensure that a variety of faults are found, resulting in more effective testing.
Dr. SHEIKH UMAR FAROOQ S. M. K. QUADRI
core