Results 61 to 70 of about 687,920 (318)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Wafer-Bonding Fabricated CMUT Device with Parylene Coating
Micromachines, 2021 The advantages of the capacitive micromachined ultrasound transducer (CMUT) technology have provided revolutionary advances in ultrasound imaging. Extensive research on CMUT devices for high-frequency medical imaging applications has been conducted ...
Changde He +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A time synchronization optimization algorithm based on SharkNet [PDF]
MATEC Web of ConferencesIn distributed measurement and control systems, high-precision time synchronization algorithm is an important guarantee to ensure the correctness of event sequence and data consistency between nodes.
Li Qiang +3 more
doaj +1 more source
Low Current Ripple Parameter-Free MPCC of Grid-Connected Inverters for PV Systems
Applied Sciences, 2023 With an emphasis placed on a low-carbon economy, photovoltaic grid-connected inverters are moving toward the center of the stage. In order to address the problems related to the strong parameter dependence of the conventional model’s predictive control ...
Zhilong Yin +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Flexural behavior of piles in high strain dynamic testing [PDF]
, 2012 The flexural vibrations of piles during dynamic tests have to be carefully investigated since it is difficult to control the alignment of the ram mass with respect to the neutral axis of the pile.
Testing and Design Methods for Deep Foundation IS-Kanazawa 2012 +2 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Novel sparse decomposition with adaptive evolutionary atoms for nonstationary signal extraction
Scientific ReportsExisting sparse decomposition techniques often rely on over-complete dictionaries and extensive prior knowledge, leading to slow computation and low efficiency.
Shuangchao Ge +7 more
doaj +1 more source