Results 81 to 90 of about 3,922 (300)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Sliding mode control based dynamic voltage restorer for voltage sag compensation

Results in Engineering
The reliability and efficiency of electrical power systems are critical for modern industries, which increasingly rely on electric machines and devices.
Ashraf K. Abdelaal, Abdullah M. Shaheen, Attia A. El-Fergany, Mohammed H. Alqahtani   +3 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

RETRACTED ARTICLE: Dynamic voltage restorer controller using grade algorithm

Cogent Engineering, 2015
This paper deals with the terminology and various issues about power quality problems. This problem occurs owing to voltage sag, swell, harmonics, and surges.
S. Deepa, M. Ranjani
doaj   +1 more source

A Novel Dynamic Voltage Restorer

, 2016
In this paper author has tried to present a new approach for integrating grid connected photo voltaic (PV) system together with a self supported dynamic voltage restorer (DVR). In this paper author has also tried to present different three topologies of DVR,the suggested three topologies are filtering schemes,dc - link capacitor and three phase four ...
openaire   +1 more source

Dispositif de protection d'un régulateur de tension série mettant en œuvre un transformateur de couplage à entrefer virtuel [PDF]

, 2014
International audienceLes régulateurs de tension série, qu'ils soient électromécaniques ou à convertisseurs statiques, constituent une solution pour améliorer la qualité de l'énergie.
Majchrzak, Virginie
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Low Power Voltage Sag Compensator

Eletrônica de Potência, 2006
The increasing use of voltage variation sensitive loads in industrial applications nowadays has brought a real concern about interruption costs and damages in complex production lines. This paper presents a power-electronic–based device which compensates
Fernando O. Martinz, Mauricio Galassi, Antonio R. Giaretta, Marco A. Oliveira, Fabiana A.T. Silva, Mario Masuda, Simão Copeliovitch, Eric R. Zanetti, Eduardo G. Lima, Josué Camargo, Se Un Ahn, Lourenço Matakas Jr., Wilson Komatsu, José A. Jardini   +13 more
doaj   +1 more source