Results 71 to 80 of about 71,473 (264)
Network Congestion Diffusion Model Considering Congestion Distribution Information
Network congestion diffusion has become the most stubborn disease and scourge of networks. With the help of widely used congestion distribution information, making full use of network capacity dynamically is a feasible and hopeful way to alleviate ...
Guoyi Wen, Ning Huang, Chunlin Wang
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Sifting fluctuation scattering from microtextured samples
Antonio Cervellino
doaj +1 more source
Neural population dynamics in human motor cortex during movements in people with ALS
The prevailing view of motor cortex holds that motor cortical neural activity represents muscle or movement parameters. However, recent studies in non-human primates have shown that neural activity does not simply represent muscle or movement parameters;
Chethan Pandarinath +9 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Mathematical Study of Learning Dynamics
Data-driven discovery of dynamics, where data is used to learn unknown dynamics, is witnessing a resurgence of interest as data and computational tools have become widespread and increasingly accessible. Advances in machine learning, data science, and neural networks are fueling new data-driven studies and rapidly changing the landscape in almost every
openaire +2 more sources
The western Pacific subtropical high (WPSH) is closely related to Asian climate. Previous studies have shown that a precise dynamical model focusing on the interaction between WPSH and other summer monsoon factors has not been developed.
Mei Hong +4 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Solid-state NMR spectroscopy at ultrahigh resolution for structural and dynamical studies of MOFs. [PDF]
Wang Q +6 more
europepmc +1 more source

