Results 91 to 100 of about 93,485 (315)

Neural population dynamics in human motor cortex during movements in people with ALS

eLife, 2015
The prevailing view of motor cortex holds that motor cortical neural activity represents muscle or movement parameters. However, recent studies in non-human primates have shown that neural activity does not simply represent muscle or movement parameters;
Chethan Pandarinath, Vikash Gilja, Christine H Blabe, Paul Nuyujukian, Anish A Sarma, Brittany L Sorice, Emad N Eskandar, Leigh R Hochberg, Jaimie M Henderson, Krishna V Shenoy   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Sifting fluctuation scattering from microtextured samples

IUCrJ, 2022
Antonio Cervellino
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Mathematical Study of Learning Dynamics

, 2021
Data-driven discovery of dynamics, where data is used to learn unknown dynamics, is witnessing a resurgence of interest as data and computational tools have become widespread and increasingly accessible. Advances in machine learning, data science, and neural networks are fueling new data-driven studies and rapidly changing the landscape in almost every
openaire   +2 more sources

Beam dynamics in NF-FFAG EMMA with dynamical maps

, 2010
Copyright @ 2010 by IPAC'10/ACFAThe Non-Scaling Fixed Field Alternating Gradient accelerator EMMA has a compact linear lattice, in which the effects of magnet fringe fields need to be modelled carefully.
Wolski, A., Edgecock, R., Giboudot, Y, Nilavalan, R, Wolski, A, Edgecock, R, Giboudot, Y.   +6 more
core  

Bifurcations in a Nonlinear Dynamical Model between Western Pacific Subtropical High Ridge Line Index and Its Summer Monsoon Impact Factors

Discrete Dynamics in Nature and Society, 2014
The western Pacific subtropical high (WPSH) is closely related to Asian climate. Previous studies have shown that a precise dynamical model focusing on the interaction between WPSH and other summer monsoon factors has not been developed.
Mei Hong, Ren Zhang, Longxia Qian, Jingjing Ge, Jian Chen   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Combined dynamical-deep learning ENSO forecasts

Nature Communications
Improving the prediction skill of El Niño-Southern Oscillation (ENSO) is of critical importance for society. Over the past half-century, significant improvements have been made in ENSO prediction.
Yipeng Chen, Yishuai Jin, Zhengyu Liu, Xingchen Shen, Xianyao Chen, Xiaopei Lin, Rong-Hua Zhang, Jing-Jia Luo, Wenjun Zhang, Wansuo Duan, Fei Zheng, Michael J. McPhaden, Lu Zhou   +12 more
doaj   +1 more source

Use of high-resolution dynamical adaptation in operational suite and research impact studies

Meteorologische Zeitschrift, 2004
The article presents a very high-resolution dynamical adaptation of the wind field with the hydrostatic version of the ALADIN model used in the operational suite, including a sensitivity study of a recent case of bura and a MAP IOP 15 case study. Bura is
Stjepan Ivatek-Šahdan, Martina Tudor
doaj   +1 more source