Results 91 to 100 of about 555,299 (300)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Network Congestion Diffusion Model Considering Congestion Distribution Information

open access: yesIEEE Access, 2019
Network congestion diffusion has become the most stubborn disease and scourge of networks. With the help of widely used congestion distribution information, making full use of network capacity dynamically is a feasible and hopeful way to alleviate ...
Guoyi Wen, Ning Huang, Chunlin Wang
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Neural population dynamics in human motor cortex during movements in people with ALS

open access: yeseLife, 2015
The prevailing view of motor cortex holds that motor cortical neural activity represents muscle or movement parameters. However, recent studies in non-human primates have shown that neural activity does not simply represent muscle or movement parameters;
Chethan Pandarinath   +9 more
doaj   +1 more source

Fourth-Order Perturbation Theory for the Half-Filled Hubbard Model in Infinite Dimensions

open access: yes, 2003
We calculate the zero-temperature self-energy to fourth-order perturbation theory in the Hubbard interaction $U$ for the half-filled Hubbard model in infinite dimensions.
Gebhard, Florian   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Bifurcations in a Nonlinear Dynamical Model between Western Pacific Subtropical High Ridge Line Index and Its Summer Monsoon Impact Factors

open access: yesDiscrete Dynamics in Nature and Society, 2014
The western Pacific subtropical high (WPSH) is closely related to Asian climate. Previous studies have shown that a precise dynamical model focusing on the interaction between WPSH and other summer monsoon factors has not been developed.
Mei Hong   +4 more
doaj   +1 more source

Physical and dynamical studies of meteors. Meteor-fragmentation and stream-distribution studies [PDF]

open access: yes
Population parameters of 275 streams including 20 additional streams in the synoptic-year sample were found by a computer technique. Some 16 percent of the sample is in these streams.
Sekanina, Z., Southworth, R. B.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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