Results 111 to 120 of about 555,299 (300)
Structure and spectroscopy of doped helium clusters using quantum Monte Carlo techniques
, 2002 We present a comparative study of the rotational characteristics of various molecule-doped 4He clusters using quantum Monte Carlo techniques. The theoretical conclusions obtained from both zero and finite temperature Monte Carlo studies confirm the ...
ALEXANDRA VIEL +3 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Technicolor and Lattice Gauge Theory [PDF]
, 2010 Technicolor and other theories of dynamical electroweak symmetry breaking invoke chiral symmetry breaking triggered by strong gauge-dynamics, analogous to that found in QCD, to explain the observed W, Z, and fermion masses. In this talk we describe why a
Chivukula, R. Sekhar +1 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Experiments on Internet Response
, 2005 This paper suggests a generalized distribution of response times to new information $\sim t^{-b}$ for human populations in the absence of deadlines.
Johansen, Anders
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On positive solutions and the Omega limit set for a class of delay differential equations
, 2012 This paper studies the positive solutions of a class of delay differential equations with two delays. These equations originate from the modeling of hematopoietic cell populations. We give a sufficient condition on the initial function for $t\leq 0$ such
B. Dorizzi +15 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Self-consistent Dynamical and Chaotic Tides in the REBOUNDx Framework
The Astrophysical JournalAt high eccentricities, tidal forcing excites vibrational modes within orbiting bodies known as dynamical tides. In this paper, we implement the coupled evolution of these modes with the body’s orbit in the REBOUNDx framework, an extension to the popular
Donald Liveoak +3 more
doaj +1 more source