Results 101 to 110 of about 93,485 (315)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Inferential vs. Dynamical Conceptions of Physics [PDF]
I contrast two possible attitudes towards a given branch of physics: as inferential (i.e., as concerned with an agent's ability to make predictions given finite information), and as dynamical (i.e., as concerned with the dynamical equations governing ...
Wallace, David, David Wallace
core
Recent studies have shown that the stimulator of interferon gene (STING) protein plays a central role in the immune system by facilitating the production of Type I interferons in cells.
Rachel, Payne +2 more
core +1 more source
Solid-state NMR spectroscopy at ultrahigh resolution for structural and dynamical studies of MOFs. [PDF]
Wang Q +6 more
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Dynamical studies of new exoplanet systems are a critical component of the discovery and characterisation process. Such studies can provide firmer constraints on the parameters of the newly discovered planets, and may even reveal that the proposed ...
Tinney, Chris +4 more
core +2 more sources
Reconstructing Kinetic Models for Dynamical Studies of Metabolism using Generative Adversarial Networks. [PDF]
Choudhury S +5 more
europepmc +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Nonlinear dynamics of networks : the groupoid formalism [PDF]
A formal theory of symmetries of networks of coupled dynamical systems, stated in terms of the group of permutations of the nodes that preserve the network topology, has existed for some time. Global network symmetries impose strong constraints on the
Ian Stewart +3 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

