Results 101 to 110 of about 93,485 (315)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Inferential vs. Dynamical Conceptions of Physics [PDF]

open access: yes, 2013
I contrast two possible attitudes towards a given branch of physics: as inferential (i.e., as concerned with an agent's ability to make predictions given finite information), and as dynamical (i.e., as concerned with the dynamical equations governing ...
Wallace, David, David Wallace
core  

All-Atom Simulations Uncover Structural and Dynamical Properties of STING Proteins in the Membrane System

open access: yes, 2022
Recent studies have shown that the stimulator of interferon gene (STING) protein plays a central role in the immune system by facilitating the production of Type I interferons in cells.
Rachel, Payne   +2 more
core   +1 more source

Solid-state NMR spectroscopy at ultrahigh resolution for structural and dynamical studies of MOFs. [PDF]

open access: yesMagn Reson Lett, 2023
Wang Q   +6 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

IAU Symposium

open access: yes, 2013
Dynamical studies of new exoplanet systems are a critical component of the discovery and characterisation process. Such studies can provide firmer constraints on the parameters of the newly discovered planets, and may even reveal that the proposed ...
Tinney, Chris   +4 more
core   +2 more sources

Reconstructing Kinetic Models for Dynamical Studies of Metabolism using Generative Adversarial Networks. [PDF]

open access: yesNat Mach Intell, 2022
Choudhury S   +5 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Nonlinear dynamics of networks : the groupoid formalism [PDF]

open access: yes, 2006
A formal theory of symmetries of networks of coupled dynamical systems, stated in terms of the group of permutations of the nodes that preserve the network topology, has existed for some time. Global network symmetries impose strong constraints on the
Ian Stewart   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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