Results 101 to 110 of about 1,894,382 (325)

Behavior as Physiology: How Dynamical-Systems Theory Could Advance Psychiatry. [PDF]

Am J Psychiatry, 2021
Salvi JD, Rauch SL, Baker JT.
europepmc   +1 more source

Dynamic Equations, Control Problems on Time Scales, and Chaotic Systems

Chaos Theory and Applications, 2023
The unification of integral and differential calculus with the calculus of finite differences has been rendered possible by providing a formal structure to study hybrid discrete-continuous dynamical systems besides offering applications in diverse fields
Martin Bohner
doaj  

Understanding and Predicting Nonlinear Turbulent Dynamical Systems with Information Theory

Atmosphere, 2019
Complex nonlinear turbulent dynamical systems are ubiquitous in many areas. Quantifying the model error and model uncertainty plays an important role in understanding and predicting complex dynamical systems.
Nan Chen, Xiao Hou, Qin Li, Yingda Li
doaj   +1 more source

A note on arithmetic topology and dynamical systems [PDF]

arXiv, 2002
We discuss analogies between the etale site of arithmetic schemes and the algebraic topology of dynamical systems. The emphasis is on Lefschetz numbers. We also discuss similarities between infinite primes in arithmetic and fixed points of dynamical systems.
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Interpretable predictions of chaotic dynamical systems using dynamical system deep learning

Scientific Reports
Making accurate predictions of chaotic dynamical systems is an essential but challenging task with many practical applications in various disciplines.
Mingyu Wang, Jianping Li
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Thermodynamics: The Unique Universal Science

Entropy, 2017
Thermodynamics is a physical branch of science that governs the thermal behavior of dynamical systems from those as simple as refrigerators to those as complex as our expanding universe.
Wassim M. Haddad
doaj   +1 more source

Applications of Dynamical Systems in Engineering [PDF]

arXiv, 2013
This paper presents the current possible applications of Dynamical Systems in Engineering. The applications of chaos, fractals have proven to be an exciting and fruitful endeavor. These applications are highly diverse ranging over such fields as Electrical, Electronics and Computer Engineering.
arxiv