Results 101 to 110 of about 3,538,316 (309)

Behavior as Physiology: How Dynamical-Systems Theory Could Advance Psychiatry. [PDF]

Am J Psychiatry, 2021
Salvi JD, Rauch SL, Baker JT.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Interpretable predictions of chaotic dynamical systems using dynamical system deep learning

Scientific Reports
Making accurate predictions of chaotic dynamical systems is an essential but challenging task with many practical applications in various disciplines.
Mingyu Wang, Jianping Li
doaj   +1 more source

Dynamic Equations, Control Problems on Time Scales, and Chaotic Systems

Chaos Theory and Applications, 2023
The unification of integral and differential calculus with the calculus of finite differences has been rendered possible by providing a formal structure to study hybrid discrete-continuous dynamical systems besides offering applications in diverse fields
Martin Bohner
doaj  

Entropy and Uncertainty

Entropy, 2008
We give a survey of the basic statistical ideas underlying the definition of entropy in information theory and their connections with the entropy in the theory of dynamical systems and in statistical mechanics.
Derek W. Robinson
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A central limit theorem for random dynamical systems

上海师范大学学报. 自然科学版, 2019
In this article, we establish a central limit theorem (CLT) for random dynamical systems (RDS), which is a supplement to the ergodic theory of random dynamical system.
LYU Kening, ZHENG Yan
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A fast–slow dynamical systems theory for the Kuramoto type phase model

, 2011
We present a fast–slow dynamical systems theory for the Kuramoto type phase model. When the order parameters are frozen, the fast system consists of independent oscillator equations, whereas the slow system describes the evolution of order parameters. We
Seung‐Yeal Ha, M. Slemrod
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source