Results 81 to 90 of about 3,133,914 (352)

Controlling complex dynamical systems based on the structure of the networks

open access: yesBiophysics and Physicobiology, 2023
Progress of molecular biology resulted in the accumulation of information on biomolecular interactions, which are complex enough to be termed as networks.
Atsushi Mochizuki
doaj   +1 more source

Equicontinuous factors, proximality and Ellis semigroup for Delone sets [PDF]

open access: yes, 2014
We discuss the application of various concepts from the theory of topological dynamical systems to Delone sets and tilings. We consider in particular, the maximal equicontinuous factor of a Delone dynamical system, the proximality relation and the ...
Aujogue, Jean-baptiste   +3 more
core   +2 more sources

Dynamical Behavior of a Rigid Body with One Fixed Point (Gyroscope). Basic Concepts and Results. Open Problems: a Review

open access: yesJournal of Applied and Computational Mechanics, 2015
The study of the dynamic behavior of a rigid body with one fixed point (gyroscope) has a long history. A number of famous mathematicians and mechanical engineers have devoted enormous time and effort to clarify the role of dynamic effects on its movement
Svetoslav Ganchev Nikolov   +1 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Theoretical Principles of Multiscale Spatiotemporal Control of Neuronal Networks: A Complex Systems Perspective

open access: yesFrontiers in Computational Neuroscience, 2018
Success in the fine control of the nervous system depends on a deeper understanding of how neural circuits control behavior. There is, however, a wide gap between the components of neural circuits and behavior.
Nima Dehghani, Nima Dehghani
doaj   +1 more source

Toric dynamical systems [PDF]

open access: yes, 2007
Toric dynamical systems are known as complex balancing mass action systems in the mathematical chemistry literature, where many of their remarkable properties have been established.
Craciun, Gheorghe   +3 more
core  

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Temporal Asymmetry, Entropic Irreversibility, and Finite-Time Thermodynamics: From Parmenides–Einstein Time-Reversal Symmetry to the Heraclitan Entropic Arrow of Time

open access: yesEntropy, 2012
In this paper, we combine the two universalisms of thermodynamics and dynamical systems theory to develop a dynamical system formalism for classical thermodynamics. Specifically, using a compartmental dynamical system energy flow model we develop a state-
Wassim M. Haddad
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

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