Results 81 to 90 of about 3,538,316 (309)

Dynamical Behavior of a Rigid Body with One Fixed Point (Gyroscope). Basic Concepts and Results. Open Problems: a Review

open access: yesJournal of Applied and Computational Mechanics, 2015
The study of the dynamic behavior of a rigid body with one fixed point (gyroscope) has a long history. A number of famous mathematicians and mechanical engineers have devoted enormous time and effort to clarify the role of dynamic effects on its movement
Svetoslav Ganchev Nikolov   +1 more
doaj   +1 more source

Systems control theory applied to natural and synthetic musical sounds [PDF]

open access: yes, 2010
Systems control theory is a far developped field which helps to study stability, estimation and control of dynamical systems. The physical behaviour of musical instruments, once described by dynamical systems, can then be controlled and numerically ...
D'Andréa-Novel, Brigitte   +1 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Theoretical Principles of Multiscale Spatiotemporal Control of Neuronal Networks: A Complex Systems Perspective

open access: yesFrontiers in Computational Neuroscience, 2018
Success in the fine control of the nervous system depends on a deeper understanding of how neural circuits control behavior. There is, however, a wide gap between the components of neural circuits and behavior.
Nima Dehghani, Nima Dehghani
doaj   +1 more source

Equicontinuous factors, proximality and Ellis semigroup for Delone sets [PDF]

open access: yes, 2014
We discuss the application of various concepts from the theory of topological dynamical systems to Delone sets and tilings. We consider in particular, the maximal equicontinuous factor of a Delone dynamical system, the proximality relation and the ...
Aujogue, Jean-baptiste   +3 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Celulární automat a CML systémy [PDF]

open access: yes, 2018
The main aim of this thesis is the study of cellular automata and discrete dynamical systems on a lattice. Both tools, cellular automata as well as dynamical systems on a lattice are introduced and elementary properties described.
Štula, Václav
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Temporal Asymmetry, Entropic Irreversibility, and Finite-Time Thermodynamics: From Parmenides–Einstein Time-Reversal Symmetry to the Heraclitan Entropic Arrow of Time

open access: yesEntropy, 2012
In this paper, we combine the two universalisms of thermodynamics and dynamical systems theory to develop a dynamical system formalism for classical thermodynamics. Specifically, using a compartmental dynamical system energy flow model we develop a state-
Wassim M. Haddad
doaj   +1 more source

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