Results 61 to 70 of about 50,252 (279)

Monitoring Mitochondrial Function in Aedes albopictus C6/36 Cell Line during Dengue Virus Infection

Insects, 2021
Aedes aegypti and Aedes albopictus mosquitoes are responsible for dengue virus (DENV) transmission in tropical and subtropical areas worldwide, where an estimated 3 billion people live at risk of DENV exposure.
María E. Santana-Román, Paola Maycotte, Salvador Uribe-Carvajal, Cristina Uribe-Alvarez, Nayeli Alvarado-Medina, Mohsin Khan, Aleem Siddiqui, Victoria Pando-Robles   +7 more
doaj   +1 more source

P2X receptor trafficking in neurons is subunit specific [PDF]

, 2002
P2X receptors within the CNS mediate excitatory synaptic transmission and also act presynaptically to modulate neurotransmitter release. We have studied the targeting and trafficking of P2X4 and P2X2 receptors heterologously expressed in cultured ...
Bobanovic, Laura K, Murrell-Lagnado, Ruth D, Royle, Stephen J   +2 more
core   +3 more sources

A dynamin‐related protein contributes to Trichomonas vaginalis hydrogenosomal fission

The FASEB Journal, 2013
Trichomonas vaginalis is a highly divergent, unicellular eukaryote of the phylum Metamonada, class Parabasalia, and the source of a common sexually transmitted infection. This parasite lacks mitochondria, but harbors an evolutionarily related organelle, the hydrogenosome.
Yael, Wexler-Cohen, Grant C, Stevens, Eran, Barnoy, Alexander M, van der Bliek, Patricia J, Johnson   +4 more
openaire   +3 more sources

Dynamin binding protein is required forXenopus laeviskidney development [PDF]

Frontiers in Physiology, 2018
ABSTRACTThe adult human kidney contains over one million nephrons, with each nephron consisting of a tube containing segments that have specialized functions in nutrient and water absorption and waste excretion. The embryonic kidney ofXenopus laevisconsists of a single functional nephron composed of regions that are analogous to those found in the ...
Bridget D. DeLay, Tanya A. Baldwin, Tanya A. Baldwin, Rachel K. Miller, Rachel K. Miller, Rachel K. Miller, Rachel K. Miller   +6 more
openaire   +3 more sources

Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission

Frontiers in Pharmacology, 2019
Background: The cardioprotective effect of propofol on ischemia-reperfusion injury (I/R injury) is partly due to suppressing apoptosis. Mitochondrial dynamics are also involved in apoptosis.
Lidong Zhao, Jinqiang Zhuang, Yihui Wang, Dandan Zhou, Dandan Zhao, Shun Zhu, Jinjun Pu, Hongyu Zhang, Ming Yin, Wenjuan Zhao, Zejian Wang, Jiang Hong   +11 more
doaj   +1 more source

A functional study of AUXILIN-LIKE1 and 2, two putative clathrin uncoating factors in Arabidopsis [PDF]

, 2018
Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which cargoes and lipids are internalized from the plasma membrane into vesicles coated with clathrin and adaptor proteins. CME is essential for many developmental and physiological
Adamowski, Maciek, De Jaeger, Geert, Friml, Jiri, Glanc, Matous, Kania, Urszula, Narasimhan, Madhumitha   +5 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1. [PDF]

, 2020
The fusion of inner mitochondrial membranes requires dynamin-like GTPases, Mgm1 in yeast and OPA1 in mammals, but how they mediate membrane fusion is poorly understood.
Hu, Junjie, Li, Lei, Lou, Zhiyong, Nunnari, Jodi, Qi, Yuanbo, Rao, Zihe, Ricketson, Derek, Sarsam, Reta, Subramanian, Kelly, Wong, Melissa, Wu, Lijie, Yan, Liming, Yu, Caiting, Zhao, Jinghua   +13 more
core  

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission [PDF]

, 2015
Defects of mitochondrial dynamics are emerging causes of neurological disease. In two children presenting with severe neurological deterioration following viral infection we identified a novel homozygous STAT2 mutation, c.1836C4A (p.Cys612Ter), using ...
Anderson, G, Cale, CM, Chalasani, A, Chan, E, Duchen, MR, Gilmour, KC, Hambleton, S, Jacques, S, Osellame, LD, Plagnol, V, Qasim, W, Rahman, S, Shahni, R, Taanman, JW, Wadatilake, Y   +14 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source