Results 181 to 190 of about 4,209 (249)

Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses. [PDF]

open access: yesPLoS Pathog
Ojha R   +21 more
europepmc   +1 more source

The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos)

open access: yesActa Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan   +13 more
wiley   +1 more source

Disulfide Crosslinking Induces Rapid Degradation of Arc/Arg3.1 via Hsp70‐Mediated Ubiquitin Ligase Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So   +7 more
wiley   +1 more source

Deep Brain Stimulation in Leigh-Like Syndrome Due to DNM1 Pathogenic Variant. [PDF]

open access: yesTremor Other Hyperkinet Mov (N Y)
Villa-Villegas L   +7 more
europepmc   +1 more source

Functional identification of two variants in unrelated Chinese patients with DNM1L-related mitochondrial disorders. [PDF]

open access: yesBMC Pediatr
Zhang Z   +10 more
europepmc   +1 more source

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