Results 81 to 90 of about 11,182 (207)

Lateralization of dynorphin gene expression in the rat striatum

open access: yes, 2008
Hemispheric lateralization is well known in the cerebral cortex, but not in subcortical structures like basal ganglia. The goal of our study was to determine whether lateralization was present in the direct and indirect striatal pathways. We studied gene
Capper-Loup, Christine   +1 more
core   +1 more source

Neuropeptides as mediators of the early-life impact on the brain; implications for alcohol use disorders

open access: yesFrontiers in Molecular Neuroscience, 2012
The brain is constantly exposed to external and internal input and to function in an ever-changing environment we are dependent on processes that enable the brain to adapt to new stimuli.
Ingrid eNylander, Erika eRoman
doaj   +1 more source

Dynorphin: friend or foe?

open access: yesPain, 2000
Pain 87 (2000) 235-239. doi:10.1016/S0304-3959(00)00360-2 ; Received by publisher: 2000-05-22 ; Harvest Date: 2016-01-04 12:22:07 ; DOI:10.1016/S0304-3959(00)00360-2 ; Page Range: 235 ...
Department of Oral Surgery, Division of Neuroscience, University of Florida College of Dentistry, P.O. Box 100416, Gainesville, FL 32610, USA ( host institution )   +2 more
openaire   +3 more sources

Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects [PDF]

open access: yes, 2006
Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect on the actions of dynorphin in these systems and dynorphin failed to produce analgesia upon ...
Moises, Hylan C.   +5 more
core   +1 more source

Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis

open access: yesScientific Reports
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 5–20% of reproductive-age women. However, the treatment of PCOS is mainly based on symptoms and not on its pathophysiology.
Gita Pratama   +6 more
doaj   +1 more source

Dynorphin Binds to P. aeruginosa In Vitro, and Enters the Bacterial Cell Cytoplasm

open access: yes, 2013
(A–C) Binding of dynorphin to P. aeruginosa; (A) negative control demonstrating no dynorphin staining when cells were not incubated with dynorphin; (B) negative control demonstrating no dynorphin staining when cell were incubated with dynorphin but ...
Gaoping Xiao (210986)   +12 more
core   +1 more source

[3H] dynorphin binding to guinea pig and rat brain

open access: yes, 1983
[3H] Dynorphin can be shown to bind to the brains of both rat and guinea pigs with approximately 50% specific binding. Characterization of the binding in terms of multiple opiate receptor types supports the kappa selectivity of dynorphin in guinea pig ...
Walker, J. Michael   +3 more
core   +1 more source

Spinal astrocytes produce and secrete dynorphin neuropeptides

open access: yes, 2013
a b s t r a c t Dynorphin peptide neurotransmitters (neuropeptides) have been implicated in spinal pain processing based on the observations that intrathecal delivery of dynorphin results in proalgesic effects and disruption of extracellular dynorphin ...
Vivian Hook   +4 more
core  

Regional distribution of dynorphin and neo-endorphin peptides in rat brain, spinal cord, and pituitary

open access: yes, 1983
Five products of the dynorphin gene--alpha-neo-endorphin, beta-neo- endorphin, dynorphin A, dynorphin A-(1-8), and dynorphin B--were measured in various regions of rat brain and in rat spinal cord and pituitary.
JD Barchas   +3 more
core   +1 more source

The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin

open access: yes, 1995
Dynorphin is one of the endogenous opioids that modulates the excitability of nociceptive (pain-sensing) neurons. We have shown recently that dynorphin blocks NMDA-activated currents directly without the participation of kappa-opioid receptors.
L Chen, LY Huang, Y Gu
core   +1 more source

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