Results 91 to 100 of about 16,897 (225)

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

open access: yes, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Acetaldehyde involvement in ethanol's postabsortive effects during early ontogeny [PDF]

open access: yes, 2013
Clinical and biomedical studies sustains the notion that early ontogeny is a vulnerable window to the impact of alcohol. Experiences with the drug during these stages increase latter disposition to prefer, use or abuse ethanol.
Abate, Paula   +2 more
core   +1 more source

Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic Plasticity through Stimulation of Microglial Release of Dynorphin A

open access: yesNeural Plasticity, 2020
Background. Visceral pain is one of the most common types of pain and particularly in the abdomen is associated with gastrointestinal diseases. Bulleyaconitine A (BAA), isolated from Aconitum bulleyanum, is prescribed in China to treat chronic pain.
Sheng-Nan Huang   +5 more
doaj   +1 more source

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink   +9 more
wiley   +1 more source

TGF-β1 enhances cardiomyogenic differentiation of skeletal muscle-derived adult primitive cells [PDF]

open access: yes, 2008
The optimal medium for cardiac differentiation of adult primitive cells remains to be established. We quantitatively compared the efficacy of IGF-1, dynorphin B, insulin, oxytocin, bFGF, and TGF-beta1 in inducing cardiomyogenic differentiation.
Abdel-Latif, Ahmed   +9 more
core   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Low Degree of Overlap Between Kisspeptin, Neurokinin B, and Dynorphin Immunoreactivities in the Infundibular Nucleus of Young Male Human Subjects Challenges the KNDy Neuron Concept. [PDF]

open access: yes, 2012
Previous immunohistochemical and in situ hybridization studies of sheep, goats, and rodents indicated that kisspeptin (KP), neurokinin B (NKB), and dynorphin A (DYN) are extensively colocalized in the hypothalamic arcuate nucleus, thus providing a basis ...
Borsay, Beáta Ágnes   +7 more
core   +1 more source

Role of movement in long-term basal ganglia changes: implications for abnormal motor responses

open access: yesFrontiers in Computational Neuroscience, 2013
Abnormal involuntary movements and dyskinesias elicited by drugs that stimulate dopamine receptors in the basal ganglia are a major issue in the management of Parkinson’s disease (PD).
Nicola eSimola   +6 more
doaj   +1 more source

Capillary HPLC Separation of Selected Neuropeptides [PDF]

open access: yes, 2012
Neuropeptides play a pivotal role in brain and peripheral nervous system function. As high performance liquid chromatography (HPLC) becomes the central tool in the separation and characterization of peptide and protein samples, its selectivity ...
Yi, Ying
core  

Rising plasma nociceptin level during development of HCC: A case report [PDF]

open access: yes, 2004
AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis.
Folhoffer, Anikó   +8 more
core   +1 more source

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