Results 111 to 120 of about 16,897 (225)

Altered expression of kisspeptin, dynorphin, and related neuropeptides in polycystic ovary syndrome: A cross-sectional study

International Journal of Reproductive BioMedicine
Background: Since kisspeptin (KISS1) in the hypothalamus is affected by the inhibitory effect of dynorphin, it raises questions about the controlled balance of these 2 neuropeptides in women with and without polycystic ovary syndrome (PCOS).
Andon Hestiantoro, Rachellina Noor Al Maghfira, Ratna Fathmasari, Ririn Rahmala Febri, Ericko Ongko Joyo, Raden Muharam, Gita Pratama, Anom Bowolaksono   +7 more
doaj   +1 more source

Structural basis of divergent substrate recognition and inhibition of human neurolysin

Scientific Reports
A zinc metallopeptidase neurolysin (Nln) processes diverse bioactive peptides to regulate signaling in the mammalian nervous system. To understand how Nln interacts with various peptides with dissimilar sequences, we determined crystal structures of Nln ...
Ke Shi, Sounak Bagchi, Jordis Bickel, Shiva H. Esfahani, Lulu Yin, Tiffany Cheng, Vardan T. Karamyan, Hideki Aihara   +7 more
doaj   +1 more source

Relationship between kisspeptin-10, neurokinin B and dynorphin A in the course of normal and delayed puberty in ewes. [PDF]

J Vet Res
Szysiak N, Kosior-Korzecka U, Greguła-Kania M, Patkowski K, Fila M, Junkuszew A.   +5 more
europepmc   +1 more source

Kappa opioid receptor control of motivated behavior revisited. [PDF]

Neuropsychopharmacology
Farahbakhsh ZZ, Siciliano CA.
europepmc   +1 more source

Multifaceted modulation of human opioid receptors by kratom alkaloids: binding affinity, functional selectivity, and allosteric activity. [PDF]

Front Pharmacol
Hemby SE, Rangel-Grimaldo M, McIntosh S, Zheng J, Flores-Bocanegra L, Graf TN, Coover RA, Oberlies NH.   +7 more
europepmc   +1 more source

Discovery of a pyridine-piperazine-based small molecule that enhances the activity of peptidase neurolysin. [PDF]

J Pharmacol Exp Ther
ElSayed ElZorkany H, Kandil H, Jayaraman S, Aly A, Esfahani SH, Patel D, Dannecker D, Maciag M, Paul A, Lowran K, Kumari S, Bose S, Ostrov DA, Wu CG, Dickson A, Abbruscato TJ, Trippier PC, Orlando BJ, Karamyan VT.   +18 more
europepmc   +1 more source

Dynorphin Deficiency in Tourette's Syndrome [PDF]

International Journal of Neuroscience, 1989
openaire   +2 more sources

Kappa Opioid Receptors Control a Stress-Sensitive Brain Circuit and Drive Cocaine Seeking. [PDF]

J Neurosci
Martinez Damonte V, Bailey LG, Thakar A, Stralka J, Brown TE, Kauer JA.   +5 more
europepmc   +1 more source

Opioids regulate the functional state of immune cells and reduce inflammatory cardiac injury: Role of opioid receptors, MRGPRX2, and TLR4. [PDF]

J Biomed Res
Gusakova SV, Sirotina M, Maslov LN, Slidnevskaya AS, Kilin M, Kurbatov BK, Kan A, Derkachev IA, Fu F.   +8 more
europepmc   +1 more source

Dysregulated Plasticity in Serotonin, Galanin, and Opioid Systems Contributes to Limbic Seizure Recruitment in Wistar Audiogenic Rat. [PDF]

J Neurochem
Camilo TA, Valentim-Lima E, de Oliveira JAC, Garcia-Cairasco N, Reis LC, Nani JV, Mecawi AS.   +6 more
europepmc   +1 more source