Results 131 to 140 of about 6,457 (202)

The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle. [PDF]

Elife
Hammond T, Choi JB, Membreño MW, Demeter J, Ng R, Bhattacharya D, Nguyen TN, Hartmann GG, Colon CI, Bossard C, Skotheim JM, Jackson PK, Pasca AM, Rubin SM, Sage J.   +14 more
europepmc   +1 more source

Nitrogen-Doped Graphene Quantum Dots Conjugated to Leucettinib-21 Rescue Differentiating Zebrafish Purkinje Cells by Inhibiting Dyrk1A Kinase. [PDF]

ACS Appl Nano Mater
Gusmão LA, Metzke A, Deau E, Meijer L, Tedesco AC, Köster RW.   +5 more
europepmc   +1 more source

The Effects of Trisomic Dyrk1a on Ts65Dn Embryonic Craniofacial Development

, 2015
poster abstractDown syndrome (DS) is caused by Trisomy 21 in humans and leads to distinctive craniofacial features in all affected individuals. The Ts65Dn mouse model of DS has orthologs of about half of the genes found on chromosome 21 and mirrors ...
Roper, Randall J., Haley, Emily, Diallo, Mariyamou   +2 more
core  

Editorial: Advances in DYRK1A syndrome: underlying mechanisms, disease models, and novel therapeutic approaches. [PDF]

Front Neurosci
Glass OK, Piton A, Pfalzer A.
europepmc   +1 more source

A Polypharmacology-Driven Approach to Alzheimer's Disease and Tauopathies: Rational Design, Synthesis and Characterization of Amino-Pyrazole-Based Multikinase (GSK-3β/FYN-α/DYRK1A) Inhibitors. [PDF]

J Med Chem
Demuro S, Russo D, Penna I, Grabska S, Grabski H, Dalle Vedove A, Valeri A, Sauvey C, Ottonello G, Summa M, Bertozzi SM, Ortega J, Bertorelli R, Storici P, Girotto S, Cruciani G, Di Martino RMC, Abagyan R, Cavalli A.   +18 more
europepmc   +1 more source

Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1A. [PDF]

Nat Commun
Chen J, Xue M, Mi S, Fu A, Chen W, Sun Y, Xia S, Ge Q, Luo J, Yu Q, Wang L, Chen S.   +11 more
europepmc   +1 more source

Correction: DYRK1A roles in human neural progenitors. [PDF]

Front Neurosci
Courraud J, Quartier A, Drouot N, Zapata-Bodalo I, Gilet J, Benchoua A, Mandel JL, Piton A.   +7 more
europepmc   +1 more source

Neuroprotective therapy after traumatic brain injury: does the window for treatment extend for months? [PDF]

Neurotherapeutics
Lynch C, Diaz-Arrastia R.
europepmc   +1 more source

Interplay between DYRK1A dosage and aneuploidy-induced neuropathology in Down syndrome. [PDF]

Commun Biol
Nambara T, Lee JY, Minami M, Okamoto S, Kawatani K, Kusakabe H, Yoshimatsu H, Hirata K, Yoshimi K, Mashimo T, Tanave A, Sumiyama K, Ozono K, Kitabatake Y.   +13 more
europepmc   +1 more source

Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish. [PDF]

Proc Natl Acad Sci U S A
Jamadagni P, Dai Y, Liu Y, Weinschutz Mendes H, Pruitt A, Khan S, Yang L, Huang TC, Huang X, Deans PJM, Balafkan N, Zhao D, Xu G, Liu Y, Li N, Wu W, Fitzpatrick SE, Neelakantan U, Chen T, Szialta C, Jin DS, Lacadie CM, Umlauf S, Papademetris X, Surovtseva YV, Brennand KJ, Wang Z, Hoffman EJ.   +27 more
europepmc   +1 more source