Results 121 to 130 of about 6,457 (202)

DYRK1A and the Cell Cycle

, 2020
The ability to halt the cell cycle is critical for cells to maintain tissue and organ size, to suppress tumors and abnormal growth, and exists as a helpful mechanism to pause the cell cycle for DNA repair.
Litovchick, MD, PhD, Larisa, Byers, Holly   +1 more
core  

Recent insights into the function of DYRK1A [PDF]

The FEBS Journal, 2010
openaire   +1 more source

Emerging role of DYRK1A as a target in cardiovascular diseases (Review). [PDF]

Mol Med Rep
Yu L, Cheng Q, Wu J.
europepmc   +1 more source

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review). [PDF]

Oncol Lett
Uría-Gómez CE, Mendieta-Zerón H, Arteaga-Vázquez J, Sandoval-Cabrera A.   +3 more
europepmc   +1 more source

DYRK1A enhances antitumor immunity in type 1 conventional dendritic cells via mTORC1 activation. [PDF]

J Clin Invest
Wang H, Jiang H, He S, Ren S, Li H, Liu W, Zhou C, Zhu P, Chen K, Cao W, Qin Y, Du D, Xiao N, Huang H, Ko CJ, Zheng Y, Wang B, Zou Q, Shi JH, Li X, Jie Z.   +20 more
europepmc   +1 more source

Genetic analysis of triplicated genes affecting sex-specific skeletal deficits in Down syndrome model mice. [PDF]

G3 (Bethesda)
Sloan K, Piner KM, Kandedura Arachchige PRN, Goodlett CR, Herault Y, Olbricht GR, Wallace JM, Roper RJ.   +7 more
europepmc   +1 more source

Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography. [PDF]

ACS Pharmacol Transl Sci
Deau E, Simon C, Hogrel G, Caillette J, Dairou J, Herault Y, Morlet B, Miyata Y, Meijer L, Lindberg MF.   +9 more
europepmc   +1 more source

Targeting DYRKs in Cardiovascular Diseases: From Biological Mechanisms to Therapeutic Translation. [PDF]

Int J Mol Sci
Jiang L, Peng S, Ma J, Liu T, Long X, Li L, Wu H.   +6 more
europepmc   +1 more source

Episignature leads to diagnosis and reclassification of DYRK1A variant in a child with syndromic neurodevelopmental disorder: a case report. [PDF]

Front Genet
Al-Younis I, Basque L, Crapoulet N, Dyack S, Del Caño-Ochoa F, Ramón-Maiques S, MacKay SB, Rzasa J, Sadikovic B, McConkey H, Ben Amor M.   +10 more
europepmc   +1 more source

DYRK1A-related intellectual disability syndrome

Česko-slovenská pediatrie, 2022
Kateřina Slabá, Hana Pálová, Petra Pokorná, Ondřej Slabý, Petra Konečná, Lucie Kolbová, Petr Jabandžiev, Dagmar Procházková   +7 more
openaire   +1 more source