Results 21 to 30 of about 495 (105)

A family study of congenital dysfibrinogenemia caused by a novel mutation in the FGA gene: A case report

Open Medicine, 2020
Congenital dysfibrinogenemia (CD) is a rare hereditary fibrinogen disorder characterized by normal fibrinogen antigen levels associated with lower functional activities.
Qiao Yingli, Zhang Qisi, Xu Poshi, Deng Yuhui   +3 more
doaj   +1 more source

Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology

Biomedicines, 2023
Chronic thromboembolic pulmonary disease results from the incomplete resolution of thrombi, leading to fibrotic obstructions. These vascular obstructions and additional microvasculopathy may lead to chronic thromboembolic pulmonary hypertension (CTEPH ...
Hakim Ghani, Joanna Pepke-Zaba
doaj   +1 more source

Thrombophilias: therapeutic employment of direct oral anticoagulants in venous hypercoagulable states

Italian Journal of Medicine, 2020
Thrombophilia or hypercoagulable state is a predisposition to form clots. Thrombophilia can be inherited or acquired, and prevalently involves venous vessels.
Federico Cacciapuoti
doaj   +1 more source

Development and validation of a novel qualitative test for plasma fibrinogen utilizing clot waveform analysis

Scientific Reports, 2022
Plasma fibrinogen is commonly examined by Clauss fibrinogen assay, which cannot distinguish between quantitative and qualitative fibrinogen anomalies. However, our previously reported Clauss fibrinogen assay utilizing clot waveform analysis (Clauss-CWA ...
Atsuo Suzuki, Nobuaki Suzuki, Takeshi Kanematsu, Sho Shinohara, Hiroshi Kurono, Nobuo Arai, Shuichi Okamoto, Naruko Suzuki, Shogo Tamura, Ryosuke Kikuchi, Akira Katsumi, Tetsuhito Kojima, Tadashi Matsushita   +12 more
doaj   +1 more source

Case Report: Co‐Occurrence of Lung Adenocarcinoma and Congenital Dysfibrinogenemia—Diagnostic and Perioperative Management Challenges

Cancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Congenital dysfibrinogenemia (CD), a rare autosomal dominant coagulation disorder, poses significant perioperative challenges in oncologic surgery due to hypofibrinogenemia and variable bleeding‐thrombosis risks. Case A 67‐year‐old woman presented with a 2.9 × 1.4 cm spiculated mass in the right middle lobe (RML) and persistent ...
He Zheng, Qingsong Wang, Mingpu Wang, Shu Luo, Yuzhen Ma, Zhengqiang Wan   +5 more
wiley   +1 more source

Laboratory and Clinical Analysis of Rare Coagulation Factor Deficiencies—A Respective Study of a Single Center from Northwest China

Clinical and Applied Thrombosis/Hemostasis
Objective Rare coagulation factor deficiencies (RCFDs) is a disease characterized by heterogeneous clinical manifestations and low prevalence. This study aimed to thoroughly analyze the clinical characteristics, routine laboratory results, and ...
Junling Li MS, Yanxia Liu, Li Yuan MS
doaj   +1 more source

Resolving Differential Diagnostic Problems in von Willebrand Disease, in Fibrinogen Disorders, in Prekallikrein Deficiency and in Hereditary Hemorrhagic Telangiectasia by Next-Generation Sequencing

Life, 2021
Diagnosis of rare bleeding disorders is challenging and there are several differential diagnostics issues. Next-generation sequencing (NGS) is a useful tool to overcome these problems.
Réka Gindele, Adrienne Kerényi, Judit Kállai, György Pfliegler, Ágota Schlammadinger, István Szegedi, Tamás Major, Zsuzsanna Szabó, Zsuzsa Bagoly, Csongor Kiss, János Kappelmayer, Zsuzsanna Bereczky   +11 more
doaj   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

American Journal of Hematology, Volume 101, Issue 1, Page 97-109, January 2026.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi, Walter Ageno, Luca Barcella, Antonio Coppola, Marcello Di Nisio, Massimo Franchini, Monia Marchetti, Rossella Marcucci, Marco Marietta, Pasquale Pignatelli, Domenico Prisco, Valerio De Stefano   +11 more
wiley   +1 more source

An acquired inhibitor that produced a delay of fibrinopeptide B release in an asymptomatic patient

Haematologica, 2007
An asymptomatic, 29-year-old woman was referred to our hospital before surgery because in the basic study of hemostasis she showed a prolonged thrombin time (TT) and a normal reptilase time (RT). She had not received any anticoagulants so, to account for
D. Llobet, M. Borrell, L. Vila, C. Vallvé, R. Felices, J. Fontcuberta   +5 more
doaj   +1 more source

Rare Coagulation Factor Deficiencies: Multicenter Experience With 188 Cases

Çocuk Dergisi, 2023
Objective: Rare factor deficiencies are a group of autosomal recessive bleeding disorders (with the exception of dysfibrinogenemia), which are characterized by the deficiency or dysfunction of one or more coagulation factors (F)I, FII, FV, FV+FVIII, FVII,
Veysel Gök, Esra Pekpak Şahinoğlu, Hüseyin Tokgöz, Fatma Türkan Mutlu, Can Acıpayam, Kamuran Karaman, Defne Ay Tuncel, Ayşe Ceyda Ören, Ayşe Şimşek, Bilal Arslan, Hatice Beyza Ünal, Alper Özcan, Ebru Yılmaz, Sinan Akbayram, Musa Karakükcü, Ahmet Fayik Öner, Ümran Çalışkan, Türkan Patıroğlu, Ekrem Ünal   +18 more
doaj   +1 more source