Results 141 to 150 of about 349,122 (350)
Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice
Annals of Neurology, EarlyView.A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi +10 more
wiley +1 more source
Clinical Effect of Poly Herbal Unani Formulation on Dyslipidemia- A Randomized Trial
, 2023 K M Khairul Alam +2 more
openalex +2 more sources
Annals of Neurology, EarlyView.Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with alteplase (TPA) increases the likelihood of FPE in basilar artery occlusion (BAO).
Dylan N. Wolman +38 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito +10 more
wiley +1 more source
Cardiovascular DiabetologyBackground The triglyceride-glucose (TyG) index is now widely recognized as a marker of insulin resistance and has been linked to the development and prognosis of atherosclerotic cardiovascular diseases (ASCVD) in numerous populations, particularly in ...
Chiara Pavanello +6 more
doaj +1 more source
Clinical guidelines as plans: An ontological theory [PDF]
, 2006 Clinical guidelines are special types of plans realized by collective agents. We provide an ontological theory of such plans that is designed to support the construction of a framework in which guideline-based information systems can be employed in the ...
Gangemi, Aldo +4 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. Although oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti +13 more
wiley +1 more source
Prevalence of and Risk Factors for Paroxysmal Atrial Fibrillation in Patients with Cardiovascular Disease but without diagnosed Atrial Fibrillation [PDF]
, 2019 学位記番号 ...
Niijima, Katsura +2 more
core
Arthritis &Rheumatology, EarlyView.Objective The phase 3 MANDARA study demonstrated noninferiority of benralizumab versus mepolizumab for remission in patients with eosinophilic granulomatosis with polyangiitis (EGPA). More benralizumab‐treated patients achieved complete withdrawal of oral glucocorticoids (OGCs).
Parameswaran K. Nair +14 more
wiley +1 more source
Per‐ and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative
Arthritis &Rheumatology, Accepted Article.Objective To explore whether biological levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting the overall effect and accounting for correlations among each PFAS – relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban +14 more
wiley +1 more source