Results 251 to 260 of about 349,122 (350)

The Epidemiology of Aortic Aneurysms: Global and Regional Trends Between 1990 and 2021

open access: yesMedicine Advances, EarlyView.
This study presents the first comprehensive global analysis of the burden and inequality of aortic aneurysm (AA) using GBD 2021 data across 204 countries and territories. While the overall global burden of AA has declined over the past three decades, our findings reveal a concerning rise in AA‐related mortality and disability‐adjusted life years (DALYs)
Jiarui Zhang   +7 more
wiley   +1 more source

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

open access: yesNano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng   +8 more
wiley   +1 more source

Fatal Pembrolizumab‐Induced Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis in a Patient With Advanced Lung Adenocarcinoma

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Po‐Chih Chang   +3 more
wiley   +1 more source

Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP‐1 Receptor Agonists: A Network Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity, EarlyView.
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella   +9 more
wiley   +1 more source

Weekly Subcutaneous VK2735, a GIP/GLP‐1 Receptor Dual Agonist, for Weight Management: Phase 2, Randomized, 13‐Week VENTURE Study

open access: yesObesity, EarlyView.
Four doses of VK2735 and a placebo group were included in the VENTURE study. Adults who were overweight or had obesity had significant weight loss when taking any dose of VK2735 for 13 weeks. More people lost at least 10% of their body weight as the dose increased.
Harold E. Bays   +9 more
wiley   +1 more source

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