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Current Opinion in Gastroenterology, 1998
Nonulcer dyspepsia, characterized by unexplained persistent or recurrent epigastric pain or discomfort, affects approximately 20% of the general population. Symptom-based diagnostic criteria, first developed by an international group of experts, have been refined in the past year in an effort to increase the applicability of the criteria (Rome II ...
J, Hammer, N J, Talley
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Nonulcer dyspepsia, characterized by unexplained persistent or recurrent epigastric pain or discomfort, affects approximately 20% of the general population. Symptom-based diagnostic criteria, first developed by an international group of experts, have been refined in the past year in an effort to increase the applicability of the criteria (Rome II ...
J, Hammer, N J, Talley
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Current Treatment Options in Gastroenterology, 2005
Idiopathic dyspepsia refers to pain and/or discomfort perceived in the epigastrium that is not secondary to organic, systemic, or metabolic diseases. Symptoms may overlap with those of gastroesophageal reflux disease and irritable bowel syndrome. Gastrointestinal motor disorders, hypersensitivity to mechanical or chemical stimuli, and psychosocial ...
STANGHELLINI, VINCENZO +5 more
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Idiopathic dyspepsia refers to pain and/or discomfort perceived in the epigastrium that is not secondary to organic, systemic, or metabolic diseases. Symptoms may overlap with those of gastroesophageal reflux disease and irritable bowel syndrome. Gastrointestinal motor disorders, hypersensitivity to mechanical or chemical stimuli, and psychosocial ...
STANGHELLINI, VINCENZO +5 more
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Medical Clinics of North America, 2014
Dyspepsia is a complex disorder with several distinct pathophysiologic mechanisms that are still poorly understood. Patients who experience dyspepsia have a high burden of disease, with significant personal and economic costs. Although serious pathology presenting as dyspepsia is rare, clinicians need to be aware of alarm features that should trigger ...
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Dyspepsia is a complex disorder with several distinct pathophysiologic mechanisms that are still poorly understood. Patients who experience dyspepsia have a high burden of disease, with significant personal and economic costs. Although serious pathology presenting as dyspepsia is rare, clinicians need to be aware of alarm features that should trigger ...
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The Netherlands Journal of Medicine, 1995
Functional dyspepsia is defined as persistent or recurrent upper abdominal pain or discomfort not explained by structural or biochemical abnormalities. In about half of the patients who present to their practitioner with chronic dyspepsia, no underlying disease is established after clinical investigation.
E M, Witteman, G N, Tytgat
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Functional dyspepsia is defined as persistent or recurrent upper abdominal pain or discomfort not explained by structural or biochemical abnormalities. In about half of the patients who present to their practitioner with chronic dyspepsia, no underlying disease is established after clinical investigation.
E M, Witteman, G N, Tytgat
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Current Opinion in Gastroenterology, 2012
A variety of organic diseases can cause dyspepsia, but most patients with epigastric pain have functional dyspepsia. As dyspepsia is common and usually has a benign cause, it is not possible to fully investigate everyone with epigastric pain. Current recommendations suggest that young patients without alarm symptoms can be treated empirically with ...
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A variety of organic diseases can cause dyspepsia, but most patients with epigastric pain have functional dyspepsia. As dyspepsia is common and usually has a benign cause, it is not possible to fully investigate everyone with epigastric pain. Current recommendations suggest that young patients without alarm symptoms can be treated empirically with ...
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BMJ, 2008
Around 25-40% of adults have chronic and recurrent dyspeptic symptoms Most patients have no structural lesions and malignancy is rare, especially in Western populations Two empirical strategies show results—a non-invasive test for H pylori and treatment of H pylori positive patients with eradication therapy (test and treat), and empirical treatment ...
ZAGARI, ROCCO MAURIZIO +2 more
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Around 25-40% of adults have chronic and recurrent dyspeptic symptoms Most patients have no structural lesions and malignancy is rare, especially in Western populations Two empirical strategies show results—a non-invasive test for H pylori and treatment of H pylori positive patients with eradication therapy (test and treat), and empirical treatment ...
ZAGARI, ROCCO MAURIZIO +2 more
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Current Opinion in Gastroenterology, 2011
This review summarizes the recent progress in the epidemiology, pathophysiology and treatment of functional dyspepsia.Epidemiological, pathophysiological and therapeutic studies continue to examine the Rome III-proposed subdivision of functional dyspepsia into epigastric pain syndrome and postprandial distress syndrome. Although epidemiological studies
Jan, Tack +2 more
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This review summarizes the recent progress in the epidemiology, pathophysiology and treatment of functional dyspepsia.Epidemiological, pathophysiological and therapeutic studies continue to examine the Rome III-proposed subdivision of functional dyspepsia into epigastric pain syndrome and postprandial distress syndrome. Although epidemiological studies
Jan, Tack +2 more
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Current Treatment Options in Gastroenterology, 2002
Dyspepsia, which is defined as pain or discomfort centered in the upper abdomen, is encountered frequently in primary care and subspecialty practice. Dyspepsia is a symptom complex caused by a heterogeneous group of disorders and diseases. A large fraction of patients with dyspepsia suffer from functional dyspepsia, in which no evidence of organic ...
Uri, Ladabaum, William D., Chey
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Dyspepsia, which is defined as pain or discomfort centered in the upper abdomen, is encountered frequently in primary care and subspecialty practice. Dyspepsia is a symptom complex caused by a heterogeneous group of disorders and diseases. A large fraction of patients with dyspepsia suffer from functional dyspepsia, in which no evidence of organic ...
Uri, Ladabaum, William D., Chey
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Current Treatment Options in Gastroenterology, 2001
There is currently no effective treatment for patients with nonulcer dyspepsia. Helicobacter pylori eradication has no beneficial effect on dyspeptic symptoms. Proton pump inhibitors are superior to placebo in the subset of patients with epigastric pain as the predominant symptom. H(2 )Receptor antagonists have no effect. Patients with dysmotility-like
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There is currently no effective treatment for patients with nonulcer dyspepsia. Helicobacter pylori eradication has no beneficial effect on dyspeptic symptoms. Proton pump inhibitors are superior to placebo in the subset of patients with epigastric pain as the predominant symptom. H(2 )Receptor antagonists have no effect. Patients with dysmotility-like
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Current Opinion in Gastroenterology, 2004
Functional dyspepsia is a common disorder, most of the time of unknown etiology and with variable pathophysiology. Therapy has been and still is largely empirical. Data from recent studies provide new clues for targeted therapy based on knowledge of etiology and pathophysiologic mechanisms.The role of Helicobacter pylori gastritis in the pathogenesis ...
Kleibeuker, JH, Thijs, JC
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Functional dyspepsia is a common disorder, most of the time of unknown etiology and with variable pathophysiology. Therapy has been and still is largely empirical. Data from recent studies provide new clues for targeted therapy based on knowledge of etiology and pathophysiologic mechanisms.The role of Helicobacter pylori gastritis in the pathogenesis ...
Kleibeuker, JH, Thijs, JC
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