Results 11 to 20 of about 48,941 (303)

Cerebellar contributions to dystonia: unraveling the role of Purkinje cells and cerebellar nuclei [PDF]

open access: yesDystonia
Dystonias are a group of neurodegenerative disorders that result in altered physiology associated with motor movements. Both the basal ganglia and the cerebellum, brain regions involved in motor learning, sensory perception integration, and reward, have ...
Nichelle N. Jackson   +3 more
doaj   +2 more sources

Clinical features and power spectral entropy of electroencephalography in Wilson's disease with dystonia

open access: yesBrain and Behavior, Volume 12, Issue 12, December 2022., 2022
WD patients with dystonia were more susceptible to suffer from low BMI and highߚlevel neurological dysfunctions. It was the first time to apply the PSE of EEG to detect the cortical synaptic activity in WD patients. The cortical activities of the WD patients with dystonia seemed to be more chaotic during the eyes‐closed and reading tasks but lower ...
Shaoru Zhang   +9 more
wiley   +1 more source

Clinical outcomes and cognitive impairments between progressive supranuclear palsy and multiple system atrophy

open access: yesBrain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Both progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) belong to atypical parkinsonian syndromes. It is important to differentiate these diseases accurately. We compared clinical outcomes and cognitive impairments between PSP and MSA. Methods Eighty‐five MSA parkinsonism type (MSA‐P) patients and 76 PSP patients
Peifei Jia   +3 more
wiley   +1 more source

A Novel Power-optimized CMOS sEMG Device with Ultra Low-noise integrated with ConvNet (VGG16) for Biomedical Applications [PDF]

open access: yes, 2023
The needle bio-potential sensors for measuring muscle and brain activity need invasive surgical targeted muscle reinnervation (TMR) and a demanding process to maintain, but surface bio-potential sensors lack clear bio-signal reading (Signal-Interference).
arxiv   +1 more source

The Dystonias [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1988
Dystonia is a difficult problem for both the clinician and the scientist. It is sufficiently common to be seen by almost all physicians, yet uncommon enough to prevent any physician from gaining broad experience in its diagnosis and treatment. Each case represents a difficult challenge even to the specialist.
E G, McGeer, P L, McGeer
openaire   +2 more sources

Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells

open access: yesDisease Models & Mechanisms, 2016
X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular models ...
Naoto Ito   +12 more
doaj   +1 more source

A mini-review of the pathophysiology of task-specific tremor: insights from electrophysiological and neuroimaging findings

open access: yesDystonia, 2023
Task-specific tremor (TST) is a specific type of tremor that occurs when performing or attempting to perform a specific task, such as writing or playing a musical instrument. The clinical entity of TST remains heterogeneous. Some TSTs can only be induced
Yih-Chih Jacinta Kuo   +1 more
doaj   +1 more source

Putaminal mosaic visualized by tyrosine hydroxylase immunohistochemistry in the human neostriatum.

open access: yesFrontiers in Neuroanatomy, 2016
Among the basal ganglia-thalamocortical circuits, the putamen plays a critical role in the ‘motor’ circuits that control voluntary movements and motor learning.
Ryoma eMorigaki, Satoshi eGoto
doaj   +1 more source

Transcriptional regulatory network for neuron-glia interactions and its implication for DYT6 dystonia

open access: yesDystonia, 2023
Advances in sequencing technologies have identified novel genes associated with inherited forms of dystonia, providing valuable insights into its genetic basis and revealing diverse genetic pathways and mechanisms involved in its pathophysiology.
Dhananjay Yellajoshyula
doaj   +1 more source

Development of a highly sensitive immunohistochemical method to detect neurochemical molecules in formalin-fixed and paraffin-embedded tissues from autopsied human brains

open access: yesFrontiers in Neuroanatomy, 2015
Immunohistochemistry (IHC) is a valuable method for identifying discrete neurochemical molecules by the interaction of target antigens with validated antibodies tagged with a visible label (e.g., peroxidase).
Satoshi eGoto   +6 more
doaj   +1 more source

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