Results 21 to 30 of about 53,170 (302)

Pain control due to botulinum toxin therapy in cervical dystonia relates to the sensorimotor integration process

Dystonia, 2023
Background: Botulinum toxin (BoNT) injections have been found to improve pain symptoms of isolated cervical dystonia (CD). In addition to muscle relaxation at the peripheral level, few studies suggest that BoNT has effects on the central brain ...
Aparna Wagle Shukla, Robert Chen, Wei Hu
doaj   +1 more source

Focal Dystonia: The Root Causes Underpinning the Yips [PDF]

, 2021
Cases of the yips have popped up from time to time in all different sports from MLB pitchers suddenly not being able to find the strike zone to professional golfers missing very short putts. A theory proposed by researchers to explain the yips is a motor
Rhoads, Brigham, Nghe, Amy, Martin, Georgia, Gibson, Eve, Loeb, Rachael, Sprague, Samuel   +5 more
core   +1 more source

The role of protein kinase R in dystonia

Dystonia, 2023
Dystonia is a progressive neurological motor disease with few treatment options and no cure. This review synthesizes the results of recent studies that implicate protein kinase R in mediating the molecular mechanisms of dystonia pathogenesis.
Benjamin Dodd, Benjamin Dodd, Stephanie L. Moon, Stephanie L. Moon   +3 more
doaj   +1 more source

Early Globus Pallidus Internus Stimulation in Pediatric Patients With Generalized Primary Dystonia: Long-Term Efficacy and Safety [PDF]

, 2010
Primary generalized dystonia presents mainly at a young age and commonly is severely disabling. The authors report the long-term follow-up (mean, 73 months; range, 50-101 months) of 5 pediatric patients (mean age at surgery 13 years; range, 8-16 years ...
Feddersen, Berend, Heinen, Florian, Borggraefe, Ingo, Bötzel, Kai, Mehrkens, Jan Hinnerk   +4 more
core   +1 more source

Striatal Vulnerability in Huntington’s Disease: Neuroprotection Versus Neurotoxicity

Brain Sciences, 2017
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat encoding an abnormally long polyglutamine tract (PolyQ) in the huntingtin (Htt) protein.
Ryoma Morigaki, Satoshi Goto
doaj   +1 more source

Regaining Motor Control in Musician's Dystonia by Restoring Sensorimotor Organization [PDF]

, 2009
Professional musicians are an excellent human model of long term effects of skilled motor training on the structure and function of the motor system.
Rosenkranz, K., Williamon, A., Williamon, A, Rothwell, JC, Rosenkranz, K, Butler, K., Rothwell, J. C., Butler, K   +7 more
core   +1 more source

Idiopathic Non-Task-Specific Upper Limb Dystonia, a Neglected Form of Dystonia [PDF]

, 2020
Objective: The objective of this study was to describe the clinical and demographic features of idiopathic non-task-specific upper limb dystonia compared with the task-specific form.
Albanese A., Scaglione C., Bertolasi L., Ceravolo R., Defazio G., Lalli S., Pisani A., Marchese R., Esposito M., Ercoli T., Eleopra R., Barone P., Fabbrini G., Mascia M. M., Italian Dystonia Registry, Liguori R., Altavista M. C., Bentivoglio A. R., Ferrazzano G., Pellicciari R., Bono F., Girlanda P., Erro R., Berardelli A.   +23 more
core   +1 more source

X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B

Neurobiology of Disease, 2017
X-linked Dystonia-Parkinsonism (XDP) is a progressive neurodegenerative disease involving the loss of medium spiny neurons within the striatum. An XDP-specific haplotype has been identified, consisting of seven sequence variants which cluster around the ...
Christine A. Vaine, David Shin, Christina Liu, William T. Hendriks, Jyotsna Dhakal, Kyle Shin, Nutan Sharma, D. Cristopher Bragg   +7 more
doaj   +1 more source

A mini-review of the pathophysiology of task-specific tremor: insights from electrophysiological and neuroimaging findings

Dystonia, 2023
Task-specific tremor (TST) is a specific type of tremor that occurs when performing or attempting to perform a specific task, such as writing or playing a musical instrument. The clinical entity of TST remains heterogeneous. Some TSTs can only be induced
Yih-Chih Jacinta Kuo, Kai-Hsiang Stanley Chen   +1 more
doaj   +1 more source

Neuroimaging in idiopathic adult-onset focal dystonia [PDF]

, 2021
We aimed to study the attitude of Italian neurologists in the use of conventional MRI in patients with idiopathic adult-onset focal dystonia. Patients were included in the Italian Dystonia Registry by experts working in different Italian centers. MRI was
Paolo Girlanda, Altavista, Maria Concetta, Maria Sofia Cotelli, Esposito, Marcello, Fabbrini, Giovanni, Marinella Turla, Roberto Ceravolo, Pierangelo Barbero, Pellicciari, Roberta, Anna Castagna, Francesca Morgante, Giovanni Cossu, Valentina Durastanti, Maurizio Zibetti, Conte, Antonella, Albanese, Alberto, Daniela Cassano, Eleopra, Roberto, Defazio, Giovanni, Salvatore Misceo, Domenico Santangelo, Brigida Minafra, Roberta Marchese, Laura Avanzino, Michele Tinazzi, Luca Maderna, Laura Bertolasi, Giulio Demonte, Anna Rita Bentivoglio, Giulia Di Lazzaro, Italian Dystonia Registry participants: Stefania Lalli, Martina Petracca, Nicola Modugno, Marco Aguggia, Valentina Oppo, Mario Coletti Moja, Grazia Devigili, Cesa Scaglione, Antonio Pisani, Roberto Erro, Giovanna Squintani, Berardelli, Alfredo, Paolo Barone, Marcello Romano, Luca Magistrelli, Sara Scannapieco, Ferrazzano, Gina, Sonia Mazzucchi, Nicola Tambasco, Di Biasio, Francesca, Ercoli, Tommaso, Bono, Francesco   +51 more
core   +1 more source