Results 41 to 50 of about 123,648 (399)

X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B

Neurobiology of Disease, 2017
X-linked Dystonia-Parkinsonism (XDP) is a progressive neurodegenerative disease involving the loss of medium spiny neurons within the striatum. An XDP-specific haplotype has been identified, consisting of seven sequence variants which cluster around the ...
Christine A. Vaine, David Shin, Christina Liu, William T. Hendriks, Jyotsna Dhakal, Kyle Shin, Nutan Sharma, D. Cristopher Bragg   +7 more
doaj   +1 more source

Disrupted sleep in dystonia depends on cerebellar function but not motor symptoms in mice

Dystonia, 2023
Although dystonia is the third most common movement disorder, patients often also experience debilitating nonmotor defects including impaired sleep.
Luis E. Salazar Leon, Luis E. Salazar Leon, Luis E. Salazar Leon, Roy V. Sillitoe, Roy V. Sillitoe, Roy V. Sillitoe, Roy V. Sillitoe, Roy V. Sillitoe   +7 more
doaj   +1 more source

FDA Approvals and Consensus Guidelines for Botulinum Toxins in the Treatment of Dystonia

Toxins, 2020
In 2016, the American Academy of Neurology (AAN) published practice guidelines for botulinum toxin (BoNT) in the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache. This article, focusing on dystonia, provides context for these
Lauren L Spiegel, J. Ostrem, Ian O. Bledsoe   +2 more
semanticscholar   +1 more source

Dystonia and paroxysmal dyskinesias: under-recognized movement disorders in domestic animals? A comparison with human dystonia/paroxysmal dyskinesias. [PDF]

, 2015
Dystonia is defined as a neurological syndrome characterized by involuntary sustained or intermittent muscle contractions causing twisting, often repetitive movements, and postures.
Albanese, Alongi, Altenmüller, Argyelan, Baird, Baizabal-Carvallo, Berardelli, Black, Bragg, Brakebusch, Breakefield, Brüggemann, Burkhard, Byrnes, Chang, Chang, Charlier, Clemmons, De Lahunta, De Ley, De Vlamynck, Defazio, Deuschl, Deuschl, Di Riso, Draper, Du, Elia, Erro, Evinger, Fahn, Forman, Fremont, Garosi, Garosi, Geiger, Geyer, Gilio, Gill, Gill, Gill, Gittis, Goodchild, Grünberg, Hallett, Hamann, Harcourt-Brown, Harvey, Herrtage, Ikoma, Jankovic, Jankovic, Jankovic, Jinnah, Jinnah, Jinnah, Kaji, Klein, Kuyper, Lohmann, Lowrie, Malone, Martlé, McCall, Meyer-Lindenberg, Meyers, Meyers, Meyers, Meyers, Müller, Nardocci, Nollet, Nollet, Obeso, Ostrander, Ozelius, Packer, Packer, Pariset, Park, Paudel, Penderis, Peters, Peterson, Prudente, Quartarone, Quartarone, Raike, Ramsey, Rascol, Richter, Richter, Richter, Richter, Richter, Ridding, Rothwell, Rothwell, Rusbridge, Sacchetto, Sanger, Shelton, Stoessl, Suls, Testoni, Thenganatt, Tolosa, Urkasemsin, Valberg, Vanhaesebrouck, Wichmann, Wilson, Wissel, Woods, Wright, Wright, Yanagisawa   +116 more
core   +2 more sources

Dystonia & tremor: A cross-sectional study of the dystonia coalition cohort.

Neurology, 2020
OBJECTIVE To assess the clinical manifestations and predictors of different types of tremors in a individuals with different types of isolated dystonia.
A. Shaikh, S. Beylergil, L. Scorr, G. Kilic-Berkmen, A. Freeman, C. Klein, Johanna Junker, Sebastian Loens, N. Brüggemann, A. Münchau, T. Bäumer, M. Vidailhet, E. Roze, C. Bonnet, J. Jankovic, J. Jimenez-shahed, Neepa Patel, L. Marsh, C. Comella, R. Barbano, B. Berman, I. Malaty, A. Wagle Shukla, S. Reich, M. LeDoux, A. Berardelli, G. Ferrazzano, N. Stover, W. Ondo, Sarah Pirio Richardson, R. Saunders-Pullman, Z. Mari, P. Agarwal, C. Adler, S. Chouinard, S. Fox, A. Brashear, D. Truong, O. Suchowersky, S. Frank, S. Factor, J. Perlmutter, H. Jinnah   +42 more
semanticscholar   +1 more source

Functional and Structural Connectivity Patterns Associated with Clinical Outcomes in Deep Brain Stimulation of the Globus Pallidus Internus for Generalized Dystonia

American Journal of Neuroradiology, 2020
BACKGROUND AND PURPOSE: Deep brain stimulation is a well-established treatment for generalized dystonia, but outcomes remain variable. Establishment of an imaging marker to guide device targeting and programming could possibly impact the efficacy of deep
L. Okromelidze, T. Tsuboi, R. Eisinger, Matthew R Burns, M. Charbel, Mohit Rana, S. Grewal, C.-Q. Lu, L. Almeida, K. Foote, M. Okun, E. Middlebrooks   +11 more
semanticscholar   +1 more source

Interdisciplinary recognizing and managing of drug‐induced tardive oromandibular dystonia: two case reports

Clinical Case Reports, 2018
Key Clinical Message Tardive dystonia is a risk factor in medical antipsychotic treatment. It often begins with repetitive involuntary jaw and tongue movements resulting in impaired chewing and detrimental effect on the dentition.
Merete Bakke, Tove Henriksen, Heidi Bryde Biernat, Torben Dalager, Eigild Møller   +4 more
doaj   +1 more source

Bradykinesia and dystonia

Dystonia, 2023
Background: Bradykinesia has been reported in patients with dystonia. Despite this, the pathophysiological mechanisms of bradykinesia in dystonia remain largely unknown.Methods: We here performed a comprehensive literature search and reviewed clinical ...
Giulia Paparella, Giulia Paparella, Andrea Guerra, Serena Galosi, Antonio Cannavacciuolo, Luca Angelini, Traian Popa, Alfredo Berardelli, Alfredo Berardelli, Matteo Bologna, Matteo Bologna   +10 more
doaj   +1 more source

What are the determinants of quality of life in people with cervical dystonia? [PDF]

, 2002
Background: Little is known about the quality of life in patients with cervical dystonia, although pain and depression are relatively common. Objective: To test the hypothesis that an individual’s ability to cope with the disease will modify the ...
Ben-Shlomo, Yoav, Camfield, Laura, Warner, Tom   +2 more
core   +2 more sources

Botulinum toxin therapy of dystonia

Journal of neural transmission, 2020
Botulinum toxin (BT) is used to treat a large number of muscle hyperactivity syndromes. Its use in dystonia, however, is still one of the most important indications for BT therapy.
D. Dressler, F. Adib Saberi, R. Rosales
semanticscholar   +1 more source