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Results 201 to 210 of about 59,671 (341)

Potential cytotoxicity of truncated slow skeletal muscle troponin T (ssTnT) in a loss of function TNNT1 myopathy mouse model

The FEBS Journal, Volume 292, Issue 20, Page 5525-5539, October 2025.
A loss of function TNNT1 myopathy mouse model with the nonsense mutation p.E180* showed potential cytotoxicity of the truncated slow troponin T fragment. The mRNA expression profile in the soleus muscle of Tnnt1‐p.E180* mice showed very different changes in comparison to that of Tnnt1‐knockout mice.
Han‐Zhong Feng, Kevin A. Strauss, Jian‐Ping Jin +2 more
wiley +1 more source

From fibro/adipogenic progenitors to adipocytes: Understanding adipogenesis in muscle degeneration for disease modulation

The Journal of Physiology, Volume 603, Issue 19, Page 5273-5297, October 1, 2025.
Abstract figure legend Fibro/adipogenic progenitors (FAPs) are cells resident in the muscle (skeletal and cardiac) niche. FAPs are active participants in the process of muscle degeneration in cardiovascular and neuromuscular diseases. Here, the accumulation of fatty and fibrous tissue is a hallmark.
Elisa Villalobos, Priyanka Mehra, Jordi Diaz‐Manera +2 more
wiley +1 more source

Improvement of Spontaneous Locomotor Activity in a Murine Model of Duchenne Muscular Dystrophy by N‐Acetylglucosamine Alone and in Combination With Prednisolone

The FASEB Journal, Volume 39, Issue 18, 30 September 2025.
Spontaneous locomotor activity of Duchenne muscular dystrophy (DMD) model mice was monitored using a cage system with external sensors. Mice received oral United State Pharmacopeia‐grade N‐acetylglucosamine (GlcNAc), prednisolone (Pred)—a current standard of care for DMD—or a combination of both.
Masahiko. S. Satoh +4 more
wiley +1 more source

Cell therapy for Duchenne muscular dystrophy: promises, challenges, and controversies. [PDF]

Cell Mol Life Sci
Łoboda A, Dulak J.
europepmc +1 more source

Different Dystrophin-like Complexes Are Expressed in Neurons and Glia [PDF]