Results 221 to 230 of about 18,651,759 (343)

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source

The diagnostic value of prostate health index combined with soluble e-cadherin for prostate cancer. [PDF]

Front Endocrinol (Lausanne)
Ahamed Y, Hossain M, Baral S, Chen J, Sun W.   +4 more
europepmc   +1 more source

E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape

Proceedings of the National Academy of Sciences of the United States of America, 2017
Kevin C. Hart, Jiongyi Tan, K. Siemers, J. Y. Sim, B. Pruitt, W. Nelson, M. Gloerich   +6 more
semanticscholar   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells. [PDF]

Oncol Rep
Zhang X, Zhang Y, Li Y.
europepmc   +1 more source

The role of γH2AX and H2AX in cervical carcinogenesis, invasion, and metastasis, and their relationship with the expression of E-cadherin

openalex   +1 more source

Molecular Docking of Interaction between E-Cadherin Protein and Conformational Structure of Cyclic Peptide ADTC3 (Ac-CADTPC-NH2) Simulated on 20 ns

, 2017
Atiatul Manna, Marlyn Dian Laksitorini, Dwi Hudiyanti, Parsaoran Siahaan   +3 more
openalex   +2 more sources

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Tumor Budding and E-Cadherin Loss as Robust Prognostic Markers in Pancreatic Ductal Adenocarcinoma: A Study in a Turkish Patient Cohort. [PDF]

Can J Gastroenterol Hepatol
Özcan TB, Pasaoglu E, Gülçiçek OB.
europepmc   +1 more source

Role of E-Cadherin in Membrane-Cortex Interaction Probed by Nanotube Extrusion [PDF]

, 2009
Erdem D. Tabdanov, Nicolas Borghi, Françoise Brochard‐Wyart, Sylvie Dufour, Jean Paul Thiery   +4 more
openalex   +1 more source