Results 221 to 230 of about 164,060 (248)
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E-Cadherin Peptide Sequence Recognition by Anti-E-Cadherin Antibody
Biochemical and Biophysical Research Communications, 1995Cadherins are calcium dependent glycoproteins involved in homophilic cell-cell adhesion. To further elucidate the interaction between cadherins we have developed an immobilized peptide ELISA to quickly scan the extracellular domains of E-cadherin. Peptides displaying antigenic reactivity to anti-E-cadherin antibody are presumably on the surface and ...
K L, Lutz, T J, Siahaan
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Expression of E-cadherin in angiomyolipoma
Human Pathology, 2012Angiomyolipoma is the most common member of perivascular epithelioid cell tumors that characteristically express myogenic and melanocytic markers. E-cadherin is a calcium-dependent cell-cell adhesion molecule that is repressed in epithelial to mesenchymal transition occurring in carcinomas.
Zhen, Wang, Qixing, Gong, Qinhe, Fan
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E-cadherin expression in human melanoma
Melanoma Research, 1996Loss of expression of E-cadherin, the major cell-cell adhesion receptor on keratinocytes, has been linked to tumour progression in various carcinomas. As E-cadherin has been reported to be expressed in cultured human melanocytes, we questioned whether loss of E-cadherin expression may also be related to melanocytic tumour progression.
Danen, E H +5 more
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2013
Hereditary Diffuse Gastric Cancer is the only gastric cancer syndrome with a proven inherited defect. So far, a single gene has been found altered in this context – CDH1 – the E-cadherin encoding gene. Other E-cadherin-associated hereditary or inheritable disorders have been identified, encompassing Hereditary Diffuse Gastric Cancer families with or ...
Joana Carvalho +2 more
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Hereditary Diffuse Gastric Cancer is the only gastric cancer syndrome with a proven inherited defect. So far, a single gene has been found altered in this context – CDH1 – the E-cadherin encoding gene. Other E-cadherin-associated hereditary or inheritable disorders have been identified, encompassing Hereditary Diffuse Gastric Cancer families with or ...
Joana Carvalho +2 more
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Hypermethylation of E-cadherin in leukemia
Blood, 2000E-cadherin gene is often termed a “metastasis suppressor” gene because the E-cadherin protein can suppress tumor cell invasion and metastasis. Inactivation of the E-cadherin gene occurs in undifferentiated solid tumors by both genetic and epigenetic mechanisms; however, the role of E-cadherin in hematologic malignancies is only now being recognized.
J R, Melki +3 more
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E‐cadherin expression in canine cutaneous histiocytoma
Veterinary Record, 2008Canine cutaneous histiocytoma is a common skin tumour of Langerhans cell origin. Langerhans cells are members of the dendritic cell family of antigen‐presenting cells and are located in the epidermis. They are unique among the dendritic cell lineage in that they express high levels of the adhesion molecule E‐cadherin.
S J, Baines, E F, McInnes, I, McConnell
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American Journal of Physiology-Renal Physiology, 2000
Ischemic epithelial cells are characterized by disruption of intercellular junctions and loss of apical-basolateral protein polarity, which are normally dependent on the integrity of the adherens junction (AJ). Biochemical analysis of both whole ischemic kidneys and ATP-depleted Madin-Darby canine kidney (MDCK) cells demonstrated a striking loss of E ...
K T, Bush, T, Tsukamoto, S K, Nigam
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Ischemic epithelial cells are characterized by disruption of intercellular junctions and loss of apical-basolateral protein polarity, which are normally dependent on the integrity of the adherens junction (AJ). Biochemical analysis of both whole ischemic kidneys and ATP-depleted Madin-Darby canine kidney (MDCK) cells demonstrated a striking loss of E ...
K T, Bush, T, Tsukamoto, S K, Nigam
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DDR1 regulates the stabilization of cell surface E‐cadherin and E‐cadherin‐mediated cell aggregation
Journal of Cellular Physiology, 2010AbstractThe stabilization of cell surface E‐cadherin is important for the maintenance of apical junction complexes and epithelial polarity. Previously, we reported that discoidin domain receptor 1 (DDR1) forms a complex with E‐cadherin at adhesive contacts; however, the regulatory role of DDR1 in the stabilization of cell surface E‐cadherin and E ...
Rajalakshmanan, Eswaramoorthy +7 more
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