Results 21 to 30 of about 174,214 (265)

E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors

Biomarker Research, 2021
Background The E-Cadherin gene (CDH1, Cadherin 1), located at 16q22.1 encodes for a calcium-dependent membranous glycoprotein with an important role in cellular adhesion and polarity maintenance.
Eike Burandt, Felix Lübbersmeyer, Natalia Gorbokon, Franziska Büscheck, Andreas M. Luebke, Anne Menz, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Frank Jacobsen, Patrick Lebok, Till Sebastian Clauditz, Guido Sauter, Ronald Simon, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Rainer Krech, David Dum, Till Krech, Andreas Holger Marx, Christian Bernreuther   +26 more
doaj   +1 more source

Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance

Nature Communications, 2023
E-cadherin is an essential cell‒cell adhesion protein that mediates canonical cadherin-catenin complex formation in epithelial lateral membranes.
Chao Kong, Xiaozhan Qu, Mingming Liu, Weiya Xu, Da Chen, Yanshen Zhang, Shan Zhang, Feng Zhu, Zhenbang Liu, Jianchao Li, Chengdong Huang, Chao Wang   +11 more
doaj   +1 more source

The deep infiltrating endometriosis tissue has lower T-cadherin, E-cadherin, progesterone receptor and oestrogen receptor than endometrioma tissue

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: To compare the T-cadherin, E-cadherin, PR and ER staining levels of deep infiltrating endometriosis (DIE) tissue, ovarian endometriomas and normal endometrial tissues. Materials and methods: DIE tissue of 24 cases, endometrioma of 30 cases and
Ismail Biyik, Uzeyir Kalkan, Sercan Simsek   +2 more
doaj   +1 more source

The Role of Epithelial and Vascular-Endothelial Cadherin in the Differentiation and Maintance of Tissue Integrity

Acta Medica, 2001
The present review has focused on the cell adhesion molecules from the cadherin superfamily, in particular on E- and VE-cadherin. In general, cadherins are a large group of cell adhesion molecules located at intercellular junctions called adherent ...
Petr Nachtigal, Andrea Gojová, Vladimír Semecký   +2 more
doaj   +1 more source

E-cadherin can replace N-cadherin during secretory-stage enamel development.

PLoS ONE, 2014
BackgroundN-cadherin is a cell-cell adhesion molecule and deletion of N-cadherin in mice is embryonic lethal. During the secretory stage of enamel development, E-cadherin is down-regulated and N-cadherin is specifically up-regulated in ameloblasts when ...
Xiaomu Guan, Felicitas B Bidlack, Nicole Stokes, John D Bartlett   +3 more
doaj   +1 more source

Vimentin is a potential prognostic factor for tongue squamous cell carcinoma among five epithelial-mesenchymal transition-related proteins. [PDF]

PLoS ONE, 2017
We aimed to investigate the association of the expression levels of five epithelial-mesenchymal transition (EMT)-related proteins (Snail, Twist, E-cadherin, N-cadherin, and Vimentin) with tumorigenesis, pathologic parameters and prognosis in tongue ...
Pei-Feng Liu, Bor-Hwang Kang, Yi-Min Wu, Ju-Hsin Sun, Liang-Ming Yen, Ting-Ying Fu, Yun-Chung Lin, Huei-Han Liou, Yaoh-Shiang Lin, Huei-Cin Sie, I-Chien Hsieh, Yu-Kai Tseng, Chih-Wen Shu, Yao-Dung Hsieh, Luo-Ping Ger   +14 more
doaj   +1 more source

The absence of early malignant changes in women subjected to Aquafilling breast augmentation on the basis of E-cadherin and N-cadherin immunohistochemical expression

Central European Journal of Immunology, 2023
The use of Aquafilling can be associated with a variety of health complications. The filler is an inflammatory process trigger at the site of tissue contact.
Michał Chalcarz, Jakub Żurawski
doaj   +1 more source

Regulation of E-cadherin [PDF]

Breast Cancer Online, 2005
Numerous studies suggest that loss of E-cadherin is necessary to induce Epithelial–mesenchymal transition (EMT) and metastasis. Snail is a major contributor to EMTs. The Snail family of zinc-finger transcription factors interact with the E-cadherin promoter to repress transcription during EMT.
Z. Yang, H. Zhang, R. Kumar
openaire   +1 more source

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

Cell Reports, 2016
E-cadherin-mediated cell-cell junctions play a prominent role in maintaining the epithelial architecture. The disruption or deregulation of these adhesions in cancer can lead to the collapse of tumor epithelia that precedes invasion and subsequent ...
Zahra Erami, David Herrmann, Sean C. Warren, Max Nobis, Ewan J. McGhee, Morghan C. Lucas, Wilfred Leung, Nadine Reischmann, Agata Mrowinska, Juliane P. Schwarz, Shereen Kadir, James R.W. Conway, Claire Vennin, Saadia A. Karim, Andrew D. Campbell, David Gallego-Ortega, Astrid Magenau, Kendelle J. Murphy, Rachel A. Ridgway, Andrew M. Law, Stacey N. Walters, Shane T. Grey, David R. Croucher, Lei Zhang, Herbert Herzog, Edna C. Hardeman, Peter W. Gunning, Christopher J. Ormandy, T.R. Jeffry Evans, Douglas Strathdee, Owen J. Sansom, Jennifer P. Morton, Kurt I. Anderson, Paul Timpson   +33 more
doaj   +1 more source

Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells. [PDF]

PLoS ONE, 2015
Epithelial-mesenchymal transition (EMT) is associated with loss of the cell-cell adhesion molecule E-cadherin and disruption of cell-cell junctions as well as with acquisition of migratory properties including reorganization of the actin cytoskeleton and
Jay Shankar, Ivan R Nabi
doaj   +1 more source