Results 21 to 30 of about 239,622 (310)
E-cadherin can replace N-cadherin during secretory-stage enamel development.
PLoS ONE, 2014 BackgroundN-cadherin is a cell-cell adhesion molecule and deletion of N-cadherin in mice is embryonic lethal. During the secretory stage of enamel development, E-cadherin is down-regulated and N-cadherin is specifically up-regulated in ameloblasts when ...
Xiaomu Guan +3 more
doaj +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2018 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]
, 2015 Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke +27 more
core +2 more sources
Cell Reports, 2016 E-cadherin-mediated cell-cell junctions play a prominent role in maintaining the epithelial architecture. The disruption or deregulation of these adhesions in cancer can lead to the collapse of tumor epithelia that precedes invasion and subsequent ...
Zahra Erami +33 more
doaj +1 more source
Central European Journal of Immunology, 2023 The use of Aquafilling can be associated with a variety of health complications. The filler is an inflammatory process trigger at the site of tissue contact.
Michał Chalcarz, Jakub Żurawski
doaj +1 more source
WAVE facilitates polarized E-cadherin transport
Molecular Biology of the Cell, 2023 The Arp2/3 nucleation-promoting factor WAVE promotes cell protrusions and apicolateral enrichment of cadherin. Does it promote cadherin trafficking? Live imaging shows that endogenous WAVE and cadherin localize to recycling endosomes and Golgi and that WAVE supports polarized sorting of cadherin.
Luigy Cordova-Burgos +5 more
openaire +2 more sources
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal [PDF]
, 2018 Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases.
Battistelli, Cecilia +14 more
core +1 more source
Expression of E-, P- and N-Cadherin and Its Clinical Significance in Cervical Squamous Cell Carcinoma and Precancerous Lesions. [PDF]
PLoS ONE, 2016 Aberrant expression of classical cadherins has been observed in tumor invasion and metastasis, but its involvement in cervical carcinogenesis and cancer progression is not clear.
Baohua Li +6 more
doaj +1 more source
The Journal of Cell Biology, 1999 E-Cadherin plays critical roles in many aspects of cell adhesion, epithelial development, and the establishment and maintenance of epithelial polarity. The fate of E-cadherin once it is delivered to the basolateral cell surface, and the mechanisms which govern its participation in adherens junctions, are not well understood. Using surface biotinylation
Tam Luan Le +2 more
openaire +1 more source
HIF-1α Contributes to Hypoxia-induced Invasion and Metastasis of Esophageal Carcinoma via Inhibiting E-cadherin and Promoting MMP-2 Expression [PDF]
, 2012 Hypoxia-inducible factor-1α (HIF-1α) has been found to enhance tumor invasion and metastasis, but no study has reported its action in esophageal carcinoma.
Cheng, Yun-Jie +7 more
core +1 more source