Results 21 to 30 of about 169,271 (266)

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

open access: yesCell Reports, 2016
E-cadherin-mediated cell-cell junctions play a prominent role in maintaining the epithelial architecture. The disruption or deregulation of these adhesions in cancer can lead to the collapse of tumor epithelia that precedes invasion and subsequent ...
Zahra Erami   +33 more
doaj   +1 more source

Vimentin is a potential prognostic factor for tongue squamous cell carcinoma among five epithelial-mesenchymal transition-related proteins. [PDF]

open access: yesPLoS ONE, 2017
We aimed to investigate the association of the expression levels of five epithelial-mesenchymal transition (EMT)-related proteins (Snail, Twist, E-cadherin, N-cadherin, and Vimentin) with tumorigenesis, pathologic parameters and prognosis in tongue ...
Pei-Feng Liu   +14 more
doaj   +1 more source

The absence of early malignant changes in women subjected to Aquafilling breast augmentation on the basis of E-cadherin and N-cadherin immunohistochemical expression

open access: yesCentral European Journal of Immunology, 2023
The use of Aquafilling can be associated with a variety of health complications. The filler is an inflammatory process trigger at the site of tissue contact.
Michał Chalcarz, Jakub Żurawski
doaj   +1 more source

Expression of E-, P- and N-Cadherin and Its Clinical Significance in Cervical Squamous Cell Carcinoma and Precancerous Lesions. [PDF]

open access: yesPLoS ONE, 2016
Aberrant expression of classical cadherins has been observed in tumor invasion and metastasis, but its involvement in cervical carcinogenesis and cancer progression is not clear.
Baohua Li   +6 more
doaj   +1 more source

Recycling of E-Cadherin [PDF]

open access: yesThe Journal of Cell Biology, 1999
E-Cadherin plays critical roles in many aspects of cell adhesion, epithelial development, and the establishment and maintenance of epithelial polarity. The fate of E-cadherin once it is delivered to the basolateral cell surface, and the mechanisms which govern its participation in adherens junctions, are not well understood. Using surface biotinylation
Tam Luan Le   +2 more
openaire   +1 more source

Progression of oral squamous cell carcinoma accompanied with reduced E-cadherin expression but not cadherin switch.

open access: yesPLoS ONE, 2012
The cadherin switch from E-cadherin to N-cadherin is considered as a hallmark of the epithelial-mesenchymal transition and progression of carcinomas. Although it enhances aggressive behaviors of adenocarcinoma cells, the significance and role of cadherin
Takashi Hashimoto   +7 more
doaj   +1 more source

Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis. [PDF]

open access: yesPLoS ONE, 2012
Alpha (α)-E-catenin is a component of the cadherin complex, and has long been thought to provide a link between cell surface cadherins and the actin skeleton.
Sumeda Nandadasa   +4 more
doaj   +1 more source

Covalent and density-controlled surface immobilization of E-cadherin for adhesion force spectroscopy.

open access: yesPLoS ONE, 2014
E-cadherin is a key cell-cell adhesion molecule but the impact of receptor density and the precise contribution of individual cadherin ectodomains in promoting cell adhesion are only incompletely understood.
Dagmar Fichtner   +8 more
doaj   +1 more source

E-cadherin expression in thymomas

open access: yesYonsei Medical Journal, 1998
For the purpose of investigating the pattern of E-cadherin (E-CD) expression in thymomas, 72 cases were immunostained using monoclonal antibody (HECD-1) and microwave-enhanced immunohistochemical method on formalin-fixed, paraffin-embedded tissue sections. The thymomas were classified according to modified Müller-Hermelink classification.
W I, Yang   +3 more
openaire   +3 more sources

Dynamics and Stability of E-Cadherin Dimers [PDF]

open access: yesBiophysical Journal, 2006
The extracellular domains of cadherins are known to play a major role in cell adhesion, although the structures involved in this process remain unclear. We have used molecular dynamics to characterize the conformational and thermodynamic properties of two of the dimer interfaces identified in E-cadherin crystals and involving the two outermost ...
Cailliez, Fabien, Lavery, Richard
openaire   +2 more sources

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