Results 91 to 100 of about 811,917 (322)

Modeling Services Acceptance Factors of Mobile Government (M-Government)

open access: yesAsia-Pacific Journal of Information Technology and Multimedia, 2012
Advancement in information and communication technologies (ICTs), particularly the rapid changes in mobile technologies have led to development of new applications and services.
Ahmad Althunibat   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

MENGUKUR ENGAGEMENT WARGA NEGARA DALAM INTERAKSI MEDIA SOSIAL (STUDI PADA 32 AKUN RESMI FACEBOOK PEMERINTAH KABUPATEN/KOTA DI JAWA TENGAH)

open access: yesJurnal Natapraja: Kajian Ilmu Administrasi Negara, 2019
The purpose of this research is to measure citizen engagement on social media interaction of 32 regencies/ municipals government official Facebook accounts in Central Java Province.To do so, a quantitative approach was conducted.
Anton Purwadi   +2 more
doaj   +1 more source

A conceptual model for semantically-based e-government portals [PDF]

open access: yes, 2005
Issues of semantic interoperability and service integration for e-government portals are the domain of interest of the present paper. We propose a Conceptual Model for One-Stop e-Government Portals based on the Semantic Web Service technology.
Cabral, Liliana   +3 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

E-GOVERNMENT SEBAGAI LAYANAN KOMUNIKASI PEMERINTAH KOTA SURABAYA (Studi Kematangan e-government Sebagai Layanan Komunikasi Government to Government, Government to Citizen, Government to Business)

open access: yesProfetik, 2018
Fenomena  pergeseran media komunikasi kearah IoT (Internet of Things) sebagai salah satu model komunikasi saat ini harus disikapi positif oleh pemerintah daerah untuk bisa berinovasi  untuk meningkatkan performance organisation management and public ...
Baharudin Noveriyanto   +4 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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