Results 81 to 90 of about 717,494 (262)
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
e-Participation Platform for Facilitating Citizens Involvement in Smart City Initiatives [PDF]
The increase in the world population and the massive migration of the population to the urban area give rise to new problems difficult to manage by the government and local authorities.
Ionuț PETRE +2 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Digital public services: Catalysts for healthcare efficiency
Healthcare systems pose a continuous concern and challenge for countries worldwide. Effective governance plays a pivotal role in managing these systems, ensuring the well-being of current and future generations.
Aleksy Kwilinski +3 more
doaj +1 more source
Adopting e-government to monitor public infrastructure projects execution in Nigeria: The public perspective. [PDF]
Afieroho P +4 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
E-Government Training to Increase Community Participation
Village E-Government is the implementation of village government through the use of the internet and computers, which is very important as a means of community participation and accountability of the village government for the administration of ...
Mukhammad Soleh +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Digital divide, e-government and trust in public service: The key role of education. [PDF]
Mesa D.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

