Results 61 to 70 of about 34,125,650 (293)
From e-government to e-governance? Towards a model of e-governance
, 2003 This paper is conceptual in nature: in it, we seek to identify the current trends of State transformation, combine them with the changes in the new information and communication technologies, and extrapolate this combination into the near future. More precisely, the goal of the paper is to analyse how the New Information and Communication Technologies ...
Finger, Matthias, Pecoud, Gaelle
openaire +4 more sources
Effectiveness of Electronic Government in the Citizen-Centric Approach in Bandung City
Mimbar, 2019 This paper aims to exploit e-government effectiveness from the perspective of users by focusing on online-based business licensing services in Bandung City.
Elisa Susanti +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
SEARCHING AND TRACKING OF LOCATION BY PROXY BASED APPROACH
ICTACT Journal on Soft Computing, 2017 Location based services became an important application in recent world. Users can search a location using smart phones and can also track the location. It is also possible for the users to retrieve information about the nearest location.
K. Nirmala +1 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Citizen adoption of E-government services
This paper considers the challenges that face the widespread adoption of E-government in Saudi Arabia. Will be using the Saudi Arabian experience as our main case study, E-government can be defined based on an existing set of requirements.
Alateyah, Sulaiman +2 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Results in ChemistryZnS nanoaggregates surface-passivated by a hydroxyl-based polymer matrix, polyvinyl alcohol (PVA), have been synthesized using a wet chemical method and an organosulphur precursor. The nanocomposite was characterized by XRD, SEM, and FTIR.
Neeta Gupta +3 more
doaj +1 more source