Results 41 to 50 of about 24,017,194 (312)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Towards Inclusive E-Government

, 2013
In this chapter, five case studies of the implementation of contact centers in Swedish municipalities are described and discussed with a focus on inclusive e-government.
Kerstin Grundén, Grundén, Kerstin,, Irene Bernhard, Bernhard, Irene,, Grundén, K.   +4 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A new normal? Streaming municipal assemblies on social media before, during and after the pandemic

Telematics and Informatics Reports
This study aims at understanding the effects that the Covid-19 lockdowns had on the streaming of municipal assemblies via social media, whether those effects persisted after the pandemic, and what were the main determinants, motivations, and consequences
Gonçalo Paiva Dias
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

ANALISIS TINGKAT IMPLEMENTASI E-GOVERNMENT PADA LEVEL KEMENTERIAN INDONESIA BERDASARKAN FRAMEWORK DELOITTE & TOUCHE

Jurnal Sistem Informasi, 2012
Saat ini layanan internet telah banyak digunakan untuk berbagai macam keperluan guna meningkatkan efektivitas dan efisiensi penggunanya. Tidak terkecuali pemerintah yang memanfaatkan internet untuk memberikan layanan dan informasi kepada masyarakatnya ...
Putu Wuri Handayani, Nurulita Prihasti Kardia   +1 more
doaj   +3 more sources

E-ServEval: a system for quality evaluation of the on-line public services [PDF]

Informatică economică, 2008
This paper describes the objectives, the general architecture and the components of the web-based system for quality evaluation of the on-line public services developed using the framework of the complex research project “System for quality ...
Alexandru BALOG, Grigore BADULESCU, Revisoara BADULESCU, Florin PETRESCU   +3 more
doaj