Results 131 to 140 of about 256,902 (295)

Evaluation of National e-Government Development Levels in Thailand

open access: yes, 2015
More than 2,000 governmental agencies and public organizations in Thailand pose a challenge in conducting evaluation of e-government development levels, especially as to be assessed and monitored along with the National Information and Communication ...
Keretho, Somnuk Bogdan   +3 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

The Human Development Index Adjusted for Efficient Resource Utilization [PDF]

open access: yes
human development index, data envelopment analysis, efficiency, congestion and scale ...
Sharma, B.   +2 more
core  

El gobierno electrónico en Ecuador

open access: yesCiencia UNEMI, 2016
In order to improve the Public Administration service delivery, approach, and relations with citizens, the Ecuadorian central government administration has developed activities based on information and communication technologies (ICTs).
Barragán-Martínez, Xavier   +1 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Electronic Administration Styles and Their Determinants. Evidence from Spanish Local Governments

open access: yesTransylvanian Review of Administrative Sciences, 2014
This paper analyzes the factors underlying the development of e-government, as an overall process, as well as of each of the three stages identified in the prior literature (e-government, egovernance and e-democracy).
José Valeriano FRÍAS-ACEITUNO   +2 more
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Analysis of Development Performance Using a Development Index Based on Factor Analysis (Old Title- Constructing Multideminsional Indexes of Economic Structure and Development) [PDF]

open access: yes
Development involves changes in social, economic and institutional structures. Quantifying development requires a large array of variables with different characteristics often highly correlated.
D.S. Prasada Rao   +3 more
core  

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