Results 141 to 150 of about 1,452,109 (316)

Digital Lags and Challenges in E-Government development in developing versus developed country: a comparative case study between Vietnam and South Korea

open access: yesJournal of International Economics and Management, 2014
Based upon several reports of United Nation in e-government recently, we analyze and pinpoint the development lag of developing countries versus developed countries in the field of e-government.
Thuy Nga Hoang   +3 more
doaj  

Power and wealth: indicators & trends in the global political economy [PDF]

open access: yes, 2012
The aim of this first ‘Power & Wealth’ Report is to kick off a new research project that aims to explore, in a historical perspective, trends in the distribution of wealth and economic power among states and global regions.
Antoniades, Andreas   +2 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Are we talking the Same Language? Challenging Complexity in Country Brand Models [PDF]

open access: yes, 2014
The purpose of this paper is to review recent research into country brand models and identify the most common and shared dimensions. Based on the literature review, this study establishes a conceptual framework to consider the complex interaction between
Mariutti, F, Tench, R
core  

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Mozambican Civil Society Within: Evaluation, Challenges, Opportunities and Action [PDF]

open access: yes, 2007
The aim of this ambitious venture is to evaluate the main dimensions of civil society's exercise of citizenship: a) its organisational Structure, covering its free and voluntary involvement, participation and contribution to society; b) the socio ...
Albertina Mucavele   +3 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

El gobierno electrónico en Ecuador

open access: yesCiencia UNEMI, 2016
In order to improve the Public Administration service delivery, approach, and relations with citizens, the Ecuadorian central government administration has developed activities based on information and communication technologies (ICTs).
Barragán-Martínez, Xavier   +1 more
doaj  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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