Results 121 to 130 of about 1,452,109 (316)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
MATEC Web of Conferences, 2016 First, it sets forth the connotation of education E-government performance evaluation in college and university, Then it illustrates its design principles as directive, complete, scientific, feasible, and development.
Ye Lijuan, Yu Fang, Zhong Jiaming
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Assessment of the results of the functioning of E-Government and digitalization of public services
Интеллект. Инновации. ИнвестицииThe digital transformation of the modern economy consists of the introduction of end-to-end digital technologies in all spheres of life in modern society and in the public administration sector.
I. S. Kalganov
doaj +1 more source
Special Libraries, December 1961 [PDF]
, 1960 Volume 52, Issue 10https://scholarworks.sjsu.edu/sla_sl_1961/1009/thumbnail ...
Special Libraries Association
core +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Role of Administrative Digitalization and Economic Development in Shaping Fiscal Efficiency: A Cross-National Analysis [PDF]
Ovidius University Annals: Economic Sciences SeriesThe paper investigates the relationship between government digitalization and economic and fiscal performance in European countries. Two multiple regressions were used with GDP(Gross Domestic Product) per capita and Tax Revenue as Percentage of GDP ...
Lăcrămioara Mansour +2 more
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source