Results 71 to 80 of about 1,452,109 (316)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

HOW EGOVERNMENT CAN CHANGE THE BUSINESS: UKRAINIAN ASPECT

open access: yesBaltic Journal of Economic Studies, 2015
The purpose of the paper is to evaluate the impact of eGovernment on business and to define the main implementation characteristics of the following systems in Ukraine. Methodology.
Volodymyr Dovhanyk
doaj  

Innovative development indices for the national economies: on the way to the “ideal” assessment of innovation processes in the countries of the world

open access: yesМодернизация, инновация, развитие
Purpose: is to develop recommendations for the construction of new indices of innovative development designed for cross-country comparisons.Methods: the conventional general scientific methods were used in the article, such as the ones of description ...
I. Danilin, A. A. Kravtsov
doaj   +1 more source

Business Climate Rankings and the California Economy [PDF]

open access: yes, 2011
Examines California's varied rankings across business climate indices and the links between economic, wage, and employment growth and the factors measured in the indices, such as productivity, taxes and costs, welfare and transfer policies, and ...
David Neumark   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Innovativeness of Poland's Economy - Conditions and Prospects for Development [PDF]

open access: yes, 2012
The structure of the article is as follows: the introduction is followed by an assessment of the level of innovativeness of Poland's economy, explanation of the reasons of poor innovativeness, and then the conditions for innovation in Poland are outlined
Kasperkiewicz Witold
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Robust Model to Measure Governance in African Countries [PDF]

open access: yes, 2009
Levels of performance of any government do matter in determining the quality of the civil society. The Ibrahim Index of African Governance developed by the Harvard Kennedy School shows how governance can be measured.
ANNONI Paola   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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