Results 71 to 80 of about 256,902 (295)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Assessing the impact of institutional environment quality on the development of e-commerce in developed and developing countries [PDF]

Problems and Perspectives in Management
This study uses the new institutional economic theory and demonstrates how the quality of the institutional environment can be correlated with the development of e-commerce in different countries.
Aksaule Zhanbozova, Tolkyn Azatbek, Marat Myrzakhmet   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Contribution of Information and Communication Technology (ICT) in Country’S H-Index [PDF]

, 2013
The aim of this study is to examine the effect of Information and Communication Technology (ICT) development on country’s scientific ranking as measured by H-index.
Farhadi, H., SALEHI, HADI, Salehi, H., Farhadi, M., ALE EBRAHIM, NADER, Ale Ebrahim, N., FARHADI, HADI, EMBI, MOHAMED AMIN, AGHAEI CHADEGANI, AREZOO, FOOLADI, MASOOD, Fooladi, M., Embi, M.A., Aehaei Chadegani, A., FARHADI, MARYAM   +13 more
core   +1 more source

Digitalisation, Digital Governance, and Eco-Innovation: Evidence from Cross-Country Data in 2022

Information
This study examines the relationship between digitalisation and eco-innovation across countries, with a particular focus on the role of digital government and digital standardisation.
Keisuke Kokubun
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

REGIONAL DATA AND KNOWLEDGE MANAGEMENT FOR THE DESIGN OF NEW E-GOVERNMENT SERVICES [PDF]

The paper introduces an innovative approach related to the sustainable regional strategy design and implementation, suggesting the process re-engineering according to the new knowledge management and citizen-oriented governance paradigm.
Mihaela MUREªAN
core  

E-GOVERNMENT PRACTICES AND ORGANISATIONAL PERFORMANCE IN MALAYSIA LOCAL GOVERNMENTS

E-Government is implemented to enhance the quality and performance of services in the public sector. Malaysia faces various issues and challenges in developing e-Government, including weaknesses in organisational performance.
Baharom, Norashikin, Othman, Zakirah, Husin, Rohana, Othman, Abdul Aziz   +3 more
core   +1 more source

Mapping Publication Trend of E-Government Development Index (Social Science Discipline Analysis)

Jurnal Ilmiah Peuradeun
This study aims to determine the research development with the Theme E-Government Development Index (EGDI) from 2003-2023. The method used in this study is qualitative with literature study. This research data source uses the Scopus database to identify research themes related to the EGDI for the 2003-2023 period, with a total of 240 article documents ...
Sukarno, Mohamad, Mutiarin, Dyah
openaire   +2 more sources