Results 91 to 100 of about 457 (204)
Issues of implementing the EAEU Digital Agenda until 2025
Вестник университетаThe target indicators of the EAEU Digital Agenda and the degree of their implementation in different countries of the organization are studied. The change in the e-Government Development Index in the EAEU countries, which is directly related to the ...
T. E. Salnikova
doaj +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
The Role of Administrative Digitalization and Economic Development in Shaping Fiscal Efficiency: A Cross-National Analysis [PDF]
Ovidius University Annals: Economic Sciences SeriesThe paper investigates the relationship between government digitalization and economic and fiscal performance in European countries. Two multiple regressions were used with GDP(Gross Domestic Product) per capita and Tax Revenue as Percentage of GDP ...
Lăcrămioara Mansour +2 more
doaj
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Assessment of the results of the functioning of E-Government and digitalization of public services
Интеллект. Инновации. ИнвестицииThe digital transformation of the modern economy consists of the introduction of end-to-end digital technologies in all spheres of life in modern society and in the public administration sector.
I. S. Kalganov
doaj +1 more source
Applied Information System and Management (AISM)E-government plays an important role in digital economic transformation by improving access to public services and driving economic growth. One implementation in West Papua Province is Rumahekraf, a digital marketing platform for creative economy players in the local region. However, the adoption of this platform is still low, and not many studies have
Nanes Fitri Rahmawati +3 more
openaire +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Al- Maǧallaẗ al-ʿarabiyyaẗ li-ʿilm al-tarǧumaẗThis research examines the correlation between e-government advancement and digital transaction expenses in Arab nations, highlighting the influence of cybersecurity maturity as a moderating factor.
Souhila Imansouren
doaj +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source