Results 91 to 100 of about 1,452,109 (316)
Strengths And Weaknesses Of The New Public Management (NPM)- Cross-Sectional And Longitudinal Analysis [PDF]
The paradigm of NPM, like its forerunners, has been trying to answer the same question for almost twenty years: how to implement policies, strategies, programs and projects, using the market-type mechanisms, so that the institutions of the state could ...
Oehler-Sincai, Iulia Monica
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Technical Progress and the Share of Labor Income [PDF]
, 2017 Changes in the labor share of national income affect inequality (Piketty 2014). This paper aims at investigating the relationship between the labor share and technical progress, based on provincial data of the People’s Republic of China (PRC) from 1978 ...
Luo, Zhi +3 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Social Justice in the EU – Index Report 2017 Social Inclusion Monitor Europe. Bertelsmann Stiftung Social Inclusion Monitor Europe 2017 [PDF]
, 2017 1. Europe is recovering not only economically, but also in the domain of social justice After years of downward movement, an upward trend in the domain of social justice is evident in the broad majority of EU member states.
Christof Schiller, Christof Schiller +3 more
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Regulatory quality and performance in EU network industries: Evidence on telecommunications, gas and electricity [PDF]
, 2009 This article provides empirical evidence on ex ante and ex post indicators of regulatory quality and the relationship between those indicators and market performance in liberalised EU-15 network industries. It finds a low level of regulatory independence
Frankfurter +9 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
مجلة العلوم و آفاق المعارفThis study aims to analyse the digital gaps in the development of e-government across African countries during the period 2020-2022, with a focus on factors that influence performance according to E-government Development Index (EGDI).
Omar Mihoubi, Brahim Sebiat
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Career advancement of the professional women in the UK construction industry: Career success factors [PDF]
The issue regarding the lack of women in the UK construction industry has become more prominent for some time, attracting government and industry wide attention due to this potential skill shortage facing the industry.
Amaratunga, Dilanthi +2 more
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