Results 91 to 100 of about 32,114,346 (248)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Development of E-Modules to Improve Higher-Order Thinking Skills in Basic Accounting Subjects at Vocational Schools

open access: yesJurnal PAJAR (Pendidikan dan Pengajaran)
This paper documents learning resources in electronic modules created to improve or explore students' Higher-Order Thinking Skills (HOTS) that are valid, practical, and effective. The research method used is Research and Development (R&D) with the ADDIE
Fitria Jayanti, Suarman, Almasdi Syhaza
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Utilization of Indonesian E-Modules Based on The ICARE Approach as An Innovation in Learning for Students

open access: yesJurnal Kependidikan
This research aims to design and implement an Indonesian e-module based on the ICARE approach, which includes the stages of Introduction, Connection, Application, Reflection, and Extension. The method in this study was research and development (R&D) with
Milya Febrirurahmy Asri   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Development of an Electronic Module (E-Module) Chemistry Based on POE (Predict, Observe, Explain) on Reaction Rate Study Materials [PDF]

open access: yes
The social restrictions that were implemented due to the COVID-19 pandemic had a profound impact on the field of education. There was an adaptation of changes from conventional to distance learning processes.
Zulfah, Sarifatul   +2 more
core   +1 more source

Grid-connected photovoltaic module and array sizing based on an iterative approach

open access: yes, 2014
This paper deals with the sizing of a simple but efficient grid-connected photovoltaic (GCPV) system to minimize the difference between the electrical energy generated by the GCPV system and the required energy.
Rotaru, M.   +2 more
core   +1 more source

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