Results 91 to 100 of about 435,103 (334)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Innovative Learning Using E-Modules

JETISH: Journal of Education Technology Information Social Sciences and Health
This research discusses the innovative use of e-modules in learning and the challenges in creating or developing creative and innovative e-modules. Education in the current digital era is undergoing a significant revolution with the adoption of technology as the main catalyst for change.
Mahardika Ardi Manggala, Partono Nyanasuryanadi, Heru Suherman   +2 more
openaire   +1 more source

Development of Guided Discovery-Based e-Module on Colligative Properties to Improve Higher Order Thinking Skills of High School Students [PDF]

, 2022
Nofrianto Nofrianto, Latisma Latisma, Desy Kurniawati, Ananda Putra   +3 more
openalex   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Development of an Interactive Digital Learning Media “E-MIREDOKS” on Redox Reaction Material

Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram
This study aims to develop and evaluate the feasibility of E-MIREDOKS (Redox Reaction Interactive E-Module) as a digital and interactive learning tool for teaching redox reactions in chemistry.
Aisyah Verolita Firdauz, Sukarmin Sukarmin   +1 more
doaj   +1 more source

Implementation of e-module endocrine system based on problem based learning (PBL) to improve scientific literacy and cognitive learning outcome [PDF]

, 2021
Jevi Milda Rahmawati, Sri Rahayu Lestari, Herawati Susilo   +2 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Integrating The Local Wisdom of Bulusan Kudus Into A P5 E-Module : A Feasibility and Practicality Study for Elementary School Students

Jurnal Kependidikan
This study aims to develop a project-based e-module for the co-curricular learning of the Pancasila Student Profile Strengthening Project (P5), focusing on the local wisdom of Bulusan, Kudus.
Ika Ari Pratiwi, Tauffiqul Lutfiyah, Much Arsyad Fardani   +2 more
doaj   +1 more source