Results 151 to 160 of about 21,662,479 (296)

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Plasma levels of E-selectin are associated with retinopathy in sickle cell disease. [PDF]

Eur J Haematol, 2023
Agouti I, Masson E, Loundou A, Jean E, Arnaud L, Abdili E, Berenger P, Lavoipierre V, Séguier J, Dignat-George F, Lacroix R, Bernit E.   +11 more
europepmc   +1 more source

The Influence of E-selectin Domains on the Binding of E-selectin to its Ligands

, 2015
Selectins are key adhesion molecules responsible for initiating a multistep process that leads a cell out of the blood circulation and into a tissue or organ.
Abu Samra, Dina Bashir Kamil, Merzaban, Jasmeen, Aleisa, Fajr A, Sakashita, Kosuke   +3 more
core  

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML. [PDF]

Leukemia, 2023
Jia Y, Zhang W, Basyal M, Chang KH, Ostermann L, Burks JK, Ly C, Mu-Mosley H, Zhang Q, Han X, Fogler WE, Magnani JL, Lesegretain A, Zal AA, Zal T, Andreeff M.   +15 more
europepmc   +1 more source

Venous and arterial thrombosis following extracorporeal photopheresis: A descriptive cohort study using a federated electronic health record network

Transfusion, EarlyView.
Abstract Background In 2018, the FDA reported VTE events in patients undergoing ECP, but these reports lacked a population‐level denominator to contextualize the risk against the known baseline thrombotic burden of the underlying conditions. Study Design and Methods We conducted a descriptive retrospective cohort study using the TriNetX federated EHR ...
Caitlin Raymond
wiley   +1 more source

Fucosylation enhances CD34⁺ hematopoietic stem cell homing and longevity via E-selectin-mediated adhesion and signaling. [PDF]

BMC Cancer
Al-Amoodi AS, Alghuneim AA, Malki JS, Nozue S, Li Y, Kai J, Zhang H, Bensaddek D, Abdel-Aziz AK, Habuchi S, Merzaban JS.   +10 more
europepmc   +1 more source

E-selectin Measurement [PDF]

, 2020
openaire   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

L- and E-selectin can recognize the same naturally occurring ligands on high endothelial venules

, 1993
The selectin family of cell adhesion molecules consists of three members, E-selectin (ELAM-1), L-selectin (LECAM-1), and P-selectin (CD62, GMP140, or PADGEM), which are all involved in binding of leukocytes to endothelial cells.
Watson, S R, Mebius, R E
core