Results 161 to 170 of about 22,586,567 (311)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Automating Trust Evaluation for Ensuring Information Quality

, 2009
Modern warfare's situation awareness and operation planning requires analyzing a vast amount of information, ranging broadly from intelligence reports to data from autonomous sensors.
Huynh, TD
core  

Corrigendum to "Long-term real-world survival outcomes with dual immune checkpoint blockade in synchronous metastatic renal cell carcinoma: implications for the design of prospective cytoreductive nephrectomy trials" [Eur. Urol. Open Sci. 83 (2026) 133-141]. [PDF]

Eur Urol Open Sci
Bickley L, Fransen van de Putte EE, van den Brink L, Marandino L, van der Mijn JC, Wilgenhof S, van Thienen JV, Haanen JBAG, Boleti E, Powles T, Zondervan PJ, Graafland NM, Tippu Z, Turajlic S, Bex A.   +14 more
europepmc   +1 more source

E-Trust in Social Commerce: A Comprehensive Review

, 2023
Pham Thi Thanh Hong, Tran Nguyen Hoang Anh   +1 more
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Correction: The effect of online hygiene information expression on customers' institutional and cognitive trust in tourist accommodation. [PDF]

Front Public Health
Zhang B, Li Y, Fang X, Huang W, Meng Q.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

E-PTES-S: Enhanced Trust Evaluation via Multidimensional Spatiotemporal Fusion and Variance-Based Stability Sequence Extraction in IoT Sensing Networks. [PDF]

Sensors (Basel)
Liu J, Yao Y, Liu X, Chen J, Li S, Lin J.   +5 more
europepmc   +1 more source

The Effect of Pulsed Magnetic Field in Combination with Electrical Muscle Stimulation for Improving Muscle Tone and Enhancing Motor Function in Hypotonic Cerebral Palsy – A Case Study

Journal Riphah College of Rehabilitation Sciences
Cerebral palsy is characterized by abnormal tone, posture and movement with multisystem involvement leading to limitation of activity. In the given case, a female patient was reported with hypotonic Cerebral palsy with complaints of floppiness and ...
Tehreem Jameel, Muhammad Haroon Asghar
doaj