Results 181 to 190 of about 211,577 (291)

SUMO E3 Ligase SlSIZ1 Facilitates Heat Tolerance in Tomato

Plant and Cell Physiology, 2018
Song Zhang, Shiju Wang, Jinlian Lv, Zhuangbin Liu, Yong Wang, Nana Ma, Q. Meng   +6 more
semanticscholar   +1 more source

E3 Ubiquitin-Protein Ligase NEDD4 [PDF]

, 2020
openaire   +1 more source

A Spatiotemporally Controlled Nanoplatform for Photothermal BRD4 Degradation Enables Synergistic Cancer Immunotherapy

Advanced Science, EarlyView.
A GSH‐responsive MOF nanoplatform acts as a Photothermolysis‐Targeting Conjugate (PTTAC). Through sophisticated step‐wise nuclear delivery, it enables NIR‐II light‐triggered photothermal degradation of BRD4. This precise strategy induces robust immunogenic cell death (ICD) and powerfully synergizes with anti‐PD‐L1 blockade to elicit a potent systemic ...
Luyi Wang, Jiasha Wu, Rui Ji, Sufeng Qiang, Yulin Shen, Yan Zuo, Shiqin Jian, Siyao Liu, Fusheng Xu, Honggang Hu, Xiaochun Hu   +10 more
wiley   +1 more source

Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin. [PDF]

Biochem Soc Trans
Basilone NT, Pimenta VM, Shaw GS.
europepmc   +1 more source

A Novel GmSIN1‐GmRNF1a‐GmCSN5a Module Determines Soybean Salt Tolerance and Yield Under Saline Soil Conditions

Advanced Science, EarlyView.
Soybean production is severely threatened by salt stress. This study reveals that the GmSIN1‐GmRNF1a‐GmCSN5a module enhances salt tolerance by stabilizing the GmSIN1 protein. GmRNF1a acts as an E3 ligase to ubiquitinate GmSIN1 for degradation, a process inhibited by GmCSN5a.
Jinlong Xu, Mengqi Shan, Xinxin Yang, Rongmei Zhao, Mengke Zhang, Guohua Bao, Lili Wang, Mingru Li, Wenjiao Zhi, Muzi Wang, Tianshi Liu, Xiaojian Zheng, Wenyu Zheng, Qing Lu, Shuo Li, Fengning Xiang   +15 more
wiley   +1 more source

RNF114, a RING E3 ligase that reads and extends the hybrid ADP-ribose-ubiquitin signal. [PDF]

EMBO J
Middleton AJ, Day CL.
europepmc   +1 more source

Regulation of the Mdm2–p53 pathway by the ubiquitin E3 ligase MARCH7

EMBO Reports, 2018
Kailiang Zhao, Yang Yang, Guang Zhang, Chenfeng Wang, Decai Wang, Mian Wu, Yide Mei   +6 more
semanticscholar   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Tissue-Resident Macrophage-Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p-TBK1. [PDF]

Adv Sci (Weinh)
An X, Li J, Wang L, Li C, Jin Z, Yao Y, Jiang M, Lin W, Wang X.   +8 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase UBR5 [PDF]

, 2020
openaire   +1 more source